X-linked hypophosphataemia (XLH) is the most frequent cause of hypophosphataemia-
associated rickets of genetic origin and is associated with high levels of the phosphaturic …

As a novel member of the two-dimensional nanomaterial family, mono-or few-layer black
phosphorus (BP) with direct bandgap and high charge carrier mobility is promising in many …

Tumor-induced osteomalacia (TIO) is an ultrarare paraneoplastic syndrome due to
overproduction of fibroblast growth factor 23 (FGF23), with profound effects on patient …

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by tumoral
production of fibroblast growth factor 23 (FGF23). The hallmark biochemical features include …

The physiological process of biomineralization is complex and deviation from it leads to a
variety of diseases. Progress in the past 10 years has enhanced understanding of the …

Serum alkaline phosphatase (ALP) and its isoenzymes reflect bone metabolism: ALP
increases the ratio of inorganic phosphate to pyrophosphate systemically and facilitates …

Rickets is a common bone disease worldwide that is associated with disturbances in
calcium and phosphate homeostasis and can lead to short stature and joint deformities …

Rickets is a disease of the growing child arising from alterations in calcium and phosphate
homeostasis resulting in impaired apoptosis of hypertrophic chondrocytes in the growth …

X-linked hypophosphatemic rickets (XLH) is the commonest inherited form of rickets. It is
caused by an impaired regulation of fibroblast growth factor 23 (FGF23) due to a PHEX gene …

Fibroblast growth factors (FGFs) are cell-signaling proteins with diverse functions in cell
development, repair, and metabolism. The human FGF family consists of 22 structurally …