The mammalian or mechanistic target of rapamycin (mTOR) pathway plays a crucial role in
regulation of cell survival, metabolism, growth and protein synthesis in response to upstream …

The epidermal growth factor receptor (EGFR) triggers the activation of many intracellular
signals that control cell proliferation, growth, survival, migration, and differentiation. Given its …

Nutrient availability is a key determinant of tumor cell behavior. While nutrient‐rich
conditions favor proliferation and tumor growth, scarcity, and particularly glutamine …

Translation is the most energy-consuming activity within cells. Due to metabolic demands
and high proliferation, cancer cells require elevated rates of protein synthesis, thus providing …

Cancer cells are characterized by quick growth and proliferation, demanding constant
supply of various nutrients. Several plasma membrane transporters delivering such …

Mammalian target of rapamycin (mTOR) serves an important role in regulating various
biological processes, including cell proliferation, metabolism, apoptosis and autophagy …

Cancer development, growth, and metastasis are highly regulated by several transcription
regulators (TRs), namely transcription factors, oncogenes, tumor-suppressor genes, and …

Acute Lymphoblastic Leukemia (ALL) is an aggressive hematologic disorder and constitutes
approximately 25% of cancer diagnoses among children and teenagers. Pediatric patients …

The capacity of cells to organize complex biochemical reactions in intracellular space is a
fundamental organizational principle of life. Key to this organization is the …

The composition of skeletal muscle fiber types affects the quality of livestock meat and
human athletic performance and health. L-arginine (Arg), a semi-essential amino acid, has …