The role of mRNA m6A methylation in the nervous system

J Li, X Yang, Z Qi, Y Sang, Y Liu, B Xu, W Liu, Z Xu… - Cell & bioscience, 2019 - Springer
Epitranscriptomics, also known as “RNA epigenetics”, is a chemical modification for RNA
regulation. Ribonucleic acid (RNA) methylation is considered to be a major discovery …

Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders

G Morris, BK Puri, AJ Walker, M Maes… - Neuroscience & …, 2019 - Elsevier
Activated immune-inflammatory, oxidative and nitrosative stress (IO&NS) pathways and
consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric …

Genetic association of major depression with atypical features and obesity-related immunometabolic dysregulations

Y Milaneschi, F Lamers, WJ Peyrot, BT Baune… - JAMA …, 2017 - jamanetwork.com
Importance The association between major depressive disorder (MDD) and obesity may
stem from shared immunometabolic mechanisms particularly evident in MDD with atypical …

Shared genetic loci between body mass index and major psychiatric disorders: a genome-wide association study

S Bahrami, NE Steen, A Shadrin, K O'Connell… - JAMA …, 2020 - jamanetwork.com
Importance People with major psychiatric disorders (MPDs) have a 10-to 20-year shorter life
span than the rest of the population, and this difference is mainly due to comorbid …

[HTML][HTML] Fto deficiency reduces anxiety-and depression-like behaviors in mice via alterations in gut microbiota

L Sun, L Ma, H Zhang, Y Cao, C Wang, N Hou… - Theranostics, 2019 - ncbi.nlm.nih.gov
Depression and obesity have high concurrence within individuals, which may be explained
by sharing the same risk factors, including disruption of the intestinal microbiota. However …

[HTML][HTML] Shared biological mechanisms of depression and obesity: focus on adipokines and lipokines

X Fu, Y Wang, F Zhao, R Cui, W **e, Q Liu… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Depression and obesity are both common disorders currently affecting public health,
frequently occurring simultaneously within individuals, and the relationship between these …

Advances in brain epitranscriptomics research and translational opportunities

F Zhang, VV Ignatova, G Ming, H Song - Molecular psychiatry, 2024 - nature.com
Various chemical modifications of all RNA transcripts, or epitranscriptomics, have emerged
as crucial regulators of RNA metabolism, attracting significant interest from both basic and …

Role of Fto on CaMKII/CREB signaling pathway of hippocampus in depressive-like behaviors induced by chronic restraint stress mice

J Shen, L Yang, W Wei - Behavioural brain research, 2021 - Elsevier
Background Major depressive disorders (MDD) is one of the most common mental illness in
the world. Recently, brain m 6 A/m (fat mass-and obesity-associated gene Fto) was found …

Effect of exposure to endocrine disrupting chemicals in obesity and neurodevelopment: The genetic and microbiota link

V Ramírez, P González-Palacios, MA Baca… - Science of The Total …, 2022 - Elsevier
Current evidence highlights the importance of the genetic component in obesity and
neurodevelopmental disorders (attention-deficit hyperactivity disorder (ADHD), autism …

Body Mass Index and risk for onset of mood and anxiety disorders in the general population: Results from the Netherlands Mental Health Survey and Incidence Study …

L de Wit, M Have, P Cuijpers, R de Graaf - BMC psychiatry, 2022 - Springer
Background Examine the onset of a clinical diagnosis of mood (major depression, dysthymia
and bipolar disorder)-and anxiety disorders (panic disorder, agoraphobia without panic …