Abstract pH-responsive polymers contain ionic functional groups as pendants in their
structure. The total number of charged groups on polymer chains determines the overall …

Although curcumin is globally recognized for its health benefits, its clinical application has
been restricted by its poor aqueous solubility and stability. To overcome these limitations …

Highlights•Chitosan is suitable for pH-sensitive gastrointestinal delivery formulation
design.•Chitosan-based formulations in response to different gastrointestinal pH …

Oral colon-targeted delivery systems (OCDSs) have attracted great attention in the delivery
of active compounds targeted to the colon for the treatment of colon and non-colon diseases …

Herein, we present a green and facile synthesis of zin oxide nanoparticles (ZnO-NPs) from
Grewia flavescens (G. flavescens). The obtained ZnO-NPs display inherent antibacterial …

Traditional Chinese medicine (TCM) has been practiced for thousands of years with a recent
increase in popularity. Despite promising biological activities of active ingredients and …

The excellent therapeutic potential of a variety of phytochemicals in different diseases has
been proven by extensive studies throughout history. However, most phytochemicals are …

Background Advances in nutriology have suggested the colon as a superior site for nutrition
absorption. Nutraceuticals, including phytochemicals, probiotics, etc., have received great …

We have employed a 2 3 factorial design approach for optimizing curcumin-loaded PLGA
nanoparticles with a specific interest in colon treatment. Curcumin-loaded PLGA …

The biggest challenge in colorectal cancer therapy is to avoid intestinal drug absorption
before reaching the colon, while focusing on tumor specific delivery with high local …