Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as
effectors of allergy. It has been only in the past two decades that mast cells have gained …

Although mast cells were discovered more than a century ago, their functions beyond their
role in allergic responses remained elusive until recently. However, there is a growing …

Mast cells (MCs) are portions of the innate and adaptive immune system derived from bone
marrow (BM) progenitors that are rich in cytoplasmic granules. MC maturation, phenotype …

Mast cells are widely distributed in tissues, particularly near surfaces exposed to the
environment. Mast cells can be activated to secrete diverse mediators and cytokines by IgE …

Background and Aims The clinical onset and severity of intestinal disorders in humans and
animals can be profoundly impacted by early life stress. Here we investigated the impact of …

Mast cells are classically viewed as effector cells of IgE-mediated allergic diseases.
However, over the last decade our understanding has been enriched about their roles in …

Klebsiella pneumoniae is a Gram-negative pathogen responsible for a wide range of
infections, including pneumonia and bacteremia, and is rapidly acquiring antibiotic …

Mast cells are multifunctional cells that initiate not only IgE-dependent allergic diseases but
also play a fundamental role in innate and adaptive immune responses to microbial …

Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

Mast cells (MCs) are crucial cells participating in both innate and adaptive immune
processes that play important roles in protecting human health and in the pathophysiology of …