Recent developments in the synthesis and applications of furopyrazoles

A Olyaei, M Sadeghpour - New Journal of Chemistry, 2020 - pubs.rsc.org
This review aims to describe the different strategies developed so far for the synthesis of furo
[2, 3-c] pyrazole, furo [3, 2-c] pyrazole, dihydrofuro [2, 3-c] pyrazole, dihydrofuro [3, 4-c] …

Conventional and microwave-assisted synthesis, antitubercular activity, and molecular docking studies of pyrazole and oxadiazole hybrids

NC Desai, K Bhatt, J Monapara, U Pandit… - ACS …, 2021 - ACS Publications
Microwave-assisted organic reaction enhancement (MORE) has become more important in
synthetic organic chemistry for efficient resource utilization. In this study, we synthesized …

Heteroannulation routes to bioactive pyrazolooxazines

KM Dawood, TA Farghaly… - Current Organic …, 2020 - ingentaconnect.com
Pyrazolo-oxazine fused systems are interesting classes of heterocyclic compounds
exhibiting pronounced biological applications such as anticancer, antitubercular, anti …

Synthesis, anticancer assessment on human breast, liver and colon carcinoma cell lines and molecular modeling study using novel pyrazolo [4, 3-c] pyridine …

NH Metwally, EA Deeb - Bioorganic Chemistry, 2018 - Elsevier
Abstract The key intermediate 3-aminopyrazolo [4, 3-c] pyridine-4, 6-dione (2) is considered
as a precursor for some novel pyrazolo [4, 3-c] pyridines 4a-c, arylhydrazopyrazolo [4, 3-c] …

Ultrasonic‐assisted condensation of aromatic and aliphatic aldehydes with 3‐(thiophen‐2‐yl)‐5‐pyrazolone: Synthesis, characterization and stereoselective …

HF Rizk, AA Noser, SA Ibrahim… - Journal of Heterocyclic …, 2022 - Wiley Online Library
A green and efficient protocol for a one‐pot condensation of 1‐(2, 4‐dinitrophenyl)‐3‐
(thiophen‐2‐yl)‐1 H‐pyrazol‐5 (4 H)‐one (1) with aromatic and aliphatic aldehydes in …

Multicomponent synthesis, in vitro cytotoxic evaluation and molecular modelling studies of polyfunctionalized pyrazolo[3,4-b]pyridine derivatives against three …

R Aggarwal, S Kumar, R Sadana… - Synthetic …, 2021 - Taylor & Francis
A series of diversely polyfunctionalized pyrazolo [3, 4-b] pyridines were synthesized by the
multicomponent reaction of phenyl/benzothiazolylhydrazine and 3-oxo-3-arylpropanenitrile …

“On-water” one-pot four-component synthesis of novel 1H-furo[2,3-c]pyrazole-4-amine derivatives

F Noruzian, A Olyaei, R Ha**asiri - Research on Chemical Intermediates, 2019 - Springer
A catalyst-free, simple and green protocol has been accomplished for the synthesis of novel
1 H-furo [2, 3-c] pyrazole-4-amines in a one-pot four-component domino reaction involving …

Cytotoxic activity against A549 human lung cancer cells and ADMET analysis of new pyrazole derivatives

A Czylkowska, M Szczesio, A Raducka… - International journal of …, 2021 - mdpi.com
Two new pyrazole derivatives, namely compound 1 and compound 2, have been
synthesized, and their biological activity has been evaluated. Monocrystals of the obtained …

Pyrazolopyrimidine and 4˗ pyrimidylpyrazolone analogues as promising novel sulfa drugs: Design, synthesis, antibacterial, antibiofilm, antiquorum agents …

HF Rizk, AMA Kamer, SA Ibrahim, E Elekhnawy… - Journal of Molecular …, 2024 - Elsevier
In the current study, we aimed at creating novel molecules with a sulfonamide group that can
be produced in simple ways. A series of novel N-arylsulfonamide pyrazolopyrimidine 3a, b …

[HTML][HTML] Ultrasound assisted synthesis, molecular structure, UV-visible assignments, MEP and Mulliken charges study of (E)-3-(4-chlorophenyl)-1-(4-methoxyphenyl) …

RS Shinde - Mat. Sci. Res. India, 2021 - materialsciencejournal.org
Present investigation deals with the synthesis and density functional theory study (DFT) of a
chalcone derivative;(E)-3-(4-chlorophenyl)-1-(4-methoxyphenyl) prop-2-en-1-one (CPMPP) …