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Subchondral bone microenvironment in osteoarthritis and pain
Y Hu, X Chen, S Wang, Y **g, J Su - Bone research, 2021 - nature.com
Osteoarthritis comprises several joint disorders characterized by articular cartilage
degeneration and persistent pain, causing disability and economic burden. The incidence of …
degeneration and persistent pain, causing disability and economic burden. The incidence of …
Cartilage calcification in osteoarthritis: mechanisms and clinical relevance
Pathological calcification of cartilage is a hallmark of osteoarthritis (OA). Calcification can be
observed both at the cartilage surface and in its deeper layers. The formation of calcium …
observed both at the cartilage surface and in its deeper layers. The formation of calcium …
Native joint-resident mesenchymal stem cells for cartilage repair in osteoarthritis
The role of native (not culture-expanded) joint-resident mesenchymal stem cells (MSCs) in
the repair of joint damage in osteoarthritis (OA) is poorly understood. MSCs differ from bone …
the repair of joint damage in osteoarthritis (OA) is poorly understood. MSCs differ from bone …
[HTML][HTML] Peripheral pain mechanisms in osteoarthritis
TL Vincent - Pain, 2020 - journals.lww.com
There is a well-established historical observation that structural joint damage by plain X-ray
correlates poorly with symptomatic disease in osteoarthritis (OA). This is often attributed to …
correlates poorly with symptomatic disease in osteoarthritis (OA). This is often attributed to …
New trends in pharmacological treatments for osteoarthritis
X Cai, S Yuan, Y Zeng, C Wang, N Yu… - Frontiers in …, 2021 - frontiersin.org
Osteoarthritis (OA) is the leading cause of function loss and disability among the elderly, with
significant burden on the individual and society. It is a severe disease for its high disability …
significant burden on the individual and society. It is a severe disease for its high disability …
[HTML][HTML] Mettl3 regulates osteogenic differentiation and alternative splicing of Vegfa in bone marrow mesenchymal stem cells
C Tian, Y Huang, Q Li, Z Feng, Q Xu - International Journal of Molecular …, 2019 - mdpi.com
Bone mesenchymal stem cells (BMSCs) can be a useful cell resource for develo**
biological treatment strategies for bone repair and regeneration, and their therapeutic …
biological treatment strategies for bone repair and regeneration, and their therapeutic …
Associations between markers of inflammation and altered pain perception mechanisms in people with knee osteoarthritis: a systematic review
P Dainese, H Mahieu, S De Mits, R Wittoek… - RMD open, 2023 - rmdopen.bmj.com
To provide an extensive review on the associations between knee inflammation and altered
pain perception mechanisms in people with knee osteoarthritis (OA). MEDLINE, Web of …
pain perception mechanisms in people with knee osteoarthritis (OA). MEDLINE, Web of …
[HTML][HTML] Osteoarthritis bone marrow lesions
Assessment and treatment of Bone Marrow Lesions (BMLs) could ultimately make step
changes to the lives of people with osteoarthritis (OA). We here review the imaging and …
changes to the lives of people with osteoarthritis (OA). We here review the imaging and …
[HTML][HTML] Best evidence rehabilitation for chronic pain part 5: osteoarthritis
Osteoarthritis (OA) is a leading cause of chronic pain and disability in older adults, which
most commonly affects the joints of the knee, hip, and hand. To date, there are no …
most commonly affects the joints of the knee, hip, and hand. To date, there are no …
Osteoclasts and osteoarthritis: novel intervention targets and therapeutic potentials during aging
H Wang, T Yuan, Y Wang, C Liu, D Li, Z Li, S Sun - Aging Cell, 2024 - Wiley Online Library
Osteoarthritis (OA), a chronic degenerative joint disease, is highly prevalent among the
aging population, and often leads to joint pain, disability, and a diminished quality of life …
aging population, and often leads to joint pain, disability, and a diminished quality of life …