Neocortical layer 1: an elegant solution to top-down and bottom-up integration

B Schuman, S Dellal, A Prönneke… - Annual review of …, 2021 - annualreviews.org
Many of our daily activities, such as riding a bike to work or reading a book in a noisy cafe,
and highly skilled activities, such as a professional playing a tennis match or a violin …

[HTML][HTML] Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity

NL Turner, T Macrina, JA Bae, R Yang, AM Wilson… - Cell, 2022 - cell.com
We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

A disinhibitory circuit motif and flexible information routing in the brain

XJ Wang, GR Yang - Current opinion in neurobiology, 2018 - Elsevier
In the mammalian neocortex, an area typically receives inputs from, and projects to, dozens
of other areas. Mechanisms are needed to flexibly route information to the right place at the …

Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas

F Scala, D Kobak, S Shan, Y Bernaerts… - Nature …, 2019 - nature.com
Abstract Layer 4 (L4) of mammalian neocortex plays a crucial role in cortical information
processing, yet a complete census of its cell types and connectivity remains elusive. Using …

Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex

SC Seeman, L Campagnola, PA Davoudian… - elife, 2018 - elifesciences.org
Generating a comprehensive description of cortical networks requires a large-scale,
systematic approach. To that end, we have begun a pipeline project using multipatch …

Synaptic connectivity to L2/3 of primary visual cortex measured by two-photon optogenetic stimulation

TA Hage, A Bosma-Moody, CA Baker, MB Kratz… - Elife, 2022 - elifesciences.org
Understanding cortical microcircuits requires thorough measurement of physiological
properties of synaptic connections formed within and between diverse subclasses of …

Structure and function of the hippocampal CA3 module

RP Sammons, M Vezir, L Moreno-Velasquez… - Proceedings of the …, 2024 - pnas.org
The hippocampal formation is crucial for learning and memory, with submodule CA3 thought
to be the substrate of pattern completion. However, the underlying synaptic and …

High-throughput microcircuit analysis of individual human brains through next-generation multineuron patch-clamp

Y Peng, FX Mittermaier, H Planert, UC Schneider… - elife, 2019 - elifesciences.org
Comparing neuronal microcircuits across different brain regions, species and individuals
can reveal common and divergent principles of network computation. Simultaneous patch …

Neocortical somatostatin neuron diversity in cognition and learning

E Park, MB Mosso, AL Barth - Trends in Neurosciences, 2025 - cell.com
Somatostatin-expressing (SST) neurons are a major class of electrophysiologically and
morphologically distinct inhibitory cells in the mammalian neocortex. Transcriptomic data …

Excitatory microcircuits within superficial layers of the medial entorhinal cortex

J Winterer, N Maier, C Wozny, P Beed, J Breustedt… - Cell reports, 2017 - cell.com
The distinctive firing pattern of grid cells in the medial entorhinal cortex (MEC) supports its
role in the representation of space. It is widely believed that the hexagonal firing field of grid …