[HTML][HTML] Fullerene: Biomedical engineers get to revisit an old friend

S Goodarzi, T Da Ros, J Conde, F Sefat, M Mozafari - Materials Today, 2017 - Elsevier
In 1985, the serendipitous discovery of fullerene triggered the research of carbon structures
into the world of symmetric nanomaterials. Consequently, Robert F. Curl, Harold W. Kroto …

C60-fullerenes as drug delivery carriers for anticancer agents: promises and hurdles

M Kumar, K Raza - Pharmaceutical nanotechnology, 2017 - ingentaconnect.com
Background: C60-fullerenes (CFs) constitute a carbon-allotropic family with cage-like fused-
ring structure, comprising of 20 hexagons and 12 pentagons. Since discovery in 1985, CFs …

C60 fullerene enhances cisplatin anticancer activity and overcomes tumor cell drug resistance

S Prylutska, R Panchuk, G Gołuński, L Skivka… - Nano Research, 2017 - Springer
We formulated and analyzed a novel nanoformulation of the anticancer drug cisplatin (Cis)
with C 60 fullerene (C 60+ Cis complex) and showed its higher toxicity toward tumor cell …

[HTML][HTML] The impact of surface functionalization on the biophysical properties of silver nanoparticles

A Borowik, K Butowska, K Konkel, R Banasiuk… - Nanomaterials, 2019 - mdpi.com
Among metal-based nanoparticles, silver nanoparticles (AgNPs) are particularly appealing
because of their stability, functionality, and documented antimicrobial properties. AgNPs …

A nanocomplex of C60 fullerene with cisplatin: design, characterization and toxicity

S Prylutska, S Politenkova… - Beilstein journal of …, 2017 - beilstein-journals.org
The self-organization of C 60 fullerene and cisplatin in aqueous solution was investigated
using the computer simulation, dynamic light scattering and atomic force microscopy …

[HTML][HTML] C60 Fullerene as an Effective Nanoplatform of Alkaloid Berberine Delivery into Leukemic Cells

A Grebinyk, S Prylutska, A Buchelnikov, N Tverdokhleb… - Pharmaceutics, 2019 - mdpi.com
A herbal alkaloid Berberine (Ber), used for centuries in Ayurvedic, Chinese, Middle-Eastern,
and native American folk medicines, is nowadays proved to function as a safe anticancer …

[HTML][HTML] Molecular interpretation of pharmaceuticals' adsorption on carbon nanomaterials: theory meets experiments

D Veclani, M Tolazzi, A Melchior - Processes, 2020 - mdpi.com
The ability of carbon-based nanomaterials (CNM) to interact with a variety of pharmaceutical
drugs can be exploited in many applications. In particular, they have been studied both as …

Toxicity of C60 fullerene–cisplatin nanocomplex against Lewis lung carcinoma cells

S Prylutska, I Grynyuk, T Skaterna, I Horak… - Archives of …, 2019 - Springer
Abstract Cisplatin (Cis-Pt) is the cytotoxic agent widely used against tumors of various origin,
but its therapeutic efficiency is substantially limited by a non-selective effect and high toxicity …

Noncovalent interaction assisted fullerene for the transportation of some brain anticancer drugs: a theoretical study

PN Samanta, KK Das - Journal of Molecular Graphics and Modelling, 2017 - Elsevier
The treatment of brain cancer like glioblastoma multiforme often uses chemotherapeutic
drugs like temozolomide, procarbazine, carmustine, and lomustine. Fullerene loaded with …

Does C60 fullerene act as a transporter of small aromatic molecules?

A Borowik, Y Prylutskyy, Ł Kawelski, O Kyzyma… - Colloids and Surfaces B …, 2018 - Elsevier
C 60 fullerene is reported to directly interact with biomolecules, such as aromatic mutagens
or anticancer drugs. Therefore, it is extensively studied for its potential application in the …