Mechano-bactericidal actions of nanostructured surfaces

DP Linklater, VA Baulin, S Juodkazis… - Nature Reviews …, 2021 - nature.com
Antibiotic resistance is a global human health threat, causing routine treatments of bacterial
infections to become increasingly difficult. The problem is exacerbated by biofilm formation …

Materials as stem cell regulators

WL Murphy, TC McDevitt, AJ Engler - Nature materials, 2014 - nature.com
The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …

Effect of the microenvironment on mesenchymal stem cell paracrine signaling: opportunities to engineer the therapeutic effect

GD Kusuma, J Carthew, R Lim… - Stem cells and …, 2017 - liebertpub.com
Cues from the extracellular environment, including physical stimuli, are well known to affect
mesenchymal stem cell (MSC) properties in terms of proliferation and differentiation. Many …

Biopolymer-based functional composites for medical applications

SB Park, E Lih, KS Park, YK Joung, DK Han - Progress in Polymer Science, 2017 - Elsevier
Over the last decade, numerous biopolymers have received more attention in medical
applications involving novel biomaterials because of their biocompatibility, biodegradability …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Modulation of immune-inflammatory responses through surface modifications of biomaterials to promote bone healing and regeneration

F Batool, H Özçelik, C Stutz… - Journal of Tissue …, 2021 - journals.sagepub.com
Control of inflammation is indispensable for optimal oral wound healing and tissue
regeneration. Several biomaterials have been used to enhance the regenerative outcomes; …

Mechano-bactericidal titanium surfaces for bone tissue engineering

TL Clainche, D Linklater, S Wong, P Le… - … applied materials & …, 2020 - ACS Publications
Despite advances in the development of bone substitutes and strict aseptic procedures, the
majority of failures in bone grafting surgery are related to nosocomial infections …

Nanotopographical surfaces for stem cell fate control: engineering mechanobiology from the bottom

W Chen, Y Shao, X Li, G Zhao, J Fu - Nano today, 2014 - Elsevier
During embryogenesis and tissue maintenance and repair in an adult organism, a myriad of
stem cells are regulated by their surrounding extracellular matrix (ECM) enriched with …

Cell sensing of physical properties at the nanoscale: Mechanisms and control of cell adhesion and phenotype

S Di Cio, JE Gautrot - Acta biomaterialia, 2016 - Elsevier
The chemistry, geometry, topography and mechanical properties of biomaterials modulate
biochemical signals (in particular ligand-receptor binding events) that control cells-matrix …

High-aspect-ratio nanostructured hydroxyapatite: towards new functionalities for a classical material

A Diez-Escudero, M Espanol, MP Ginebra - Chemical Science, 2024 - pubs.rsc.org
Hydroxyapatite-based materials have been widely used in countless applications, such as
bone regeneration, catalysis, air and water purification or protein separation. Recently, much …