Interactions between dietary carbohydrate and metformin: implications on energy sensing, insulin signaling pathway, glycolipid metabolism and glucose tolerance in …

C Xu, WB Liu, DD Zhang, XF Cao, HJ Shi, XF Li - Aquaculture, 2018 - Elsevier
A 12-week feeding trial was performed to evaluate the effects of metformin on growth
performance, energy sensing, insulin signaling pathway, glycolipid metabolism and glucose …

The gastro protective effects of Cibotium barometz hair on ethanol-induced gastric ulcer in Sprague-Dawley rats

NS Al-Wajeeh, M Hajerezaie, SM Noor… - BMC Veterinary …, 2016 - Springer
Background Cibotium barometz is a medical herb used traditionally in the Malaysian
peninsula for several ailments, including gastric ulcer. The aim of this study was assessment …

Gastroprotective activity of Hypericum perforatum extract in ethanol-induced gastric mucosal injury in Wistar rats: A possible involvement of H+/K+ ATPase α inhibition

SH Sofi, SM Nuraddin, ZA Amin, HA Al-Bustany… - Heliyon, 2020 - cell.com
Hypericum perforatum (HP) is a plant native to Asia and Europe. It has been documented to
enclose medical effects against many disorders such as anxiety, depression and burns. This …

AdipoRon, an orally active, synthetic agonist of AdipoR1 and AdipoR2 receptors has gastroprotective effect in experimentally induced gastric ulcers in mice

H Zatorski, M Salaga, M Zielińska, K Majchrzak… - Molecules, 2021 - mdpi.com
Introduction: Adiponectin is a hormone secreted by adipocytes, which exhibits insulin-
sensitizing and anti-inflammatory properties and acts through adiponectin receptors …

Metformin Inefficiency to Lower Lipids in Vitamin B12 Deficient HepG2 Cells Is Alleviated via Adiponectin-AMPK Axis

J Boachie, V Zammit, P Saravanan… - Nutrients, 2023 - mdpi.com
Background: Prolonged metformin treatment decreases vitamin B12 (B12) levels, whereas
low B12 is associated with dyslipidaemia. Some studies have reported that metformin has …

[HTML][HTML] Ulcer prevention effect of 3, 4, 5-tihydroxy-N0-[(2-methyl-1H-Indol-3yl) Methylidene] Benzohydrazide in HCl/Ethanol-Induced gastric mucosal damage in rats

F Tayeby, AAA Salman, S Kamran… - International Journal of …, 2017 - ncbi.nlm.nih.gov
Abstract The newly synthesized, 3, 4, 5-Trihydroxy-N 0-[(2-methyl-1H-indol-3-yl)-
methylidene] benzohydrazide (TIBH), is an indole and gallic acid derivative. The aim of this …

Anti H. pylori, anti-secretory and gastroprotective effects of Thymus vulgaris on ethanol-induced gastric ulcer in Sprague Dawley rats

STJ Balaky - Plos one, 2024 - journals.plos.org
The objectives of the present study were to evaluate the acute toxicity, gastroprotective,
therapeutic, anti-inflammatory and anti H. pylori activities of T. vulgaris total plant extract …

Alendronate-induced gastric damage in normoglycemic and hyperglycemic rats is reversed by metformin

IRSG Nolêto, B Iles, MS Alencar, ALF Lopes… - European Journal of …, 2019 - Elsevier
Alendronate is a bisphosphonate widely used for the treatment of osteoporosis; however,
one of its main adverse reactions is gastric ulcer. Metformin is an oral antihyperglycemic …

Obesity-related gastrointestinal disorders

E Lin, AJ Yeoh, V Popov - Nutrition, Weight, and Digestive Health: The …, 2022 - Springer
Obesity is a known risk factor for the development of metabolic syndrome and mortality
associated with a wide range of diseases including those of the gastrointestinal system …

Potential effect of medicinal plants on the prevention of gastric ulcer: Mechanism of actions

S Wasman Qader, L Suan Chua… - Journal of Pharmacy …, 2022 - eprints.tiu.edu.iq
Medicinal plants have been widely studied to identify plant-based anti-gastric ulcer
medicines. The mechanism of gastroprotective action is important to discover the potential …