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Insight into the regulatory mechanism of β‐arrestin2 and its emerging role in diseases
M Qi, TT Chen, L Li, PP Gao, N Li… - British Journal of …, 2024 - Wiley Online Library
β‐arrestin2, a member of the arrestin family, mediates the desensitization and internalization
of most G protein‐coupled receptors (GPCRs) and functions as a scaffold protein in …
of most G protein‐coupled receptors (GPCRs) and functions as a scaffold protein in …
[HTML][HTML] Utilization of biased G protein-coupled receptor signaling towards development of safer and personalized therapeutics
G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological
processes. Therefore, approximately 40% of currently prescribed drugs have targeted this …
processes. Therefore, approximately 40% of currently prescribed drugs have targeted this …
The association of ARRB1 polymorphisms with response to antidepressant treatment in depressed patients
Introduction: β-arrestin 1, a protein encoded by ARRB1 involved in receptor signaling, is a
potential biomarker for the response to antidepressant drug (ATD) treatment in depression …
potential biomarker for the response to antidepressant drug (ATD) treatment in depression …
Analysis of the deleterious single-nucleotide polymorphisms associated with antidepressant efficacy in major depressive disorder
Major depressive disorder (MDD) is a serious mental disease with negative effects on both
mental and physical health of the patient. Currently, antidepressants are among the major …
mental and physical health of the patient. Currently, antidepressants are among the major …
Arrestin mutations: Some cause diseases, others promise cure
Arrestins play a key role in homologous desensitization of G protein-coupled receptors
(GPCRs) and regulate several other vital signaling pathways in cells. Considering the critical …
(GPCRs) and regulate several other vital signaling pathways in cells. Considering the critical …
Motor stereotypic behavior was associated with immune response in macaques: Insight from transcriptome and gut microbiota analysis
X Pan, F Liu, Y Song, H Wang, L Wang, H Qiu… - Frontiers in …, 2021 - frontiersin.org
Motor stereotypic behaviors (MSBs) are common in captive rhesus macaques (Macaca
mulatta) and human with psychiatric diseases. However, large gaps remain in our …
mulatta) and human with psychiatric diseases. However, large gaps remain in our …
Light-Sensitive Membrane Proteins as Tools to Generate Precision Treatments
E Lesca - The Journal of membrane biology, 2020 - Springer
Introduction by Ana-Nicoleta Bondar, Biophysics Section Head Editor This issue of the
Journal of Membrane Biology inaugurates Up-and-Coming Scientist, in which investigators …
Journal of Membrane Biology inaugurates Up-and-Coming Scientist, in which investigators …
A common goal, a common path: Shared mechanisms between psilocybin and SSRI antidepressant actions?
AB Wulff - 2023 - search.proquest.com
Abstract Major Depressive Disorder is a prevalent and debilitating mental illness. While
heterogenous in pathogenesis, symptomatology, and neurobiology, it is marked by reduced …
heterogenous in pathogenesis, symptomatology, and neurobiology, it is marked by reduced …
Novel strategies for pharmacogenetic and metabolomic analysis of antidepressant treatment response in depression
K Chappell - 2023 - theses.hal.science
Introduction Major Depressive Disorder (MDD) is a global burden whose treatment with
antidepressant drugs (ATDs) is modestly effective. Predictors of ATD response may help …
antidepressant drugs (ATDs) is modestly effective. Predictors of ATD response may help …