Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation

SX Gu, T Tyagi, K Jain, VW Gu, SH Lee… - Nature Reviews …, 2021 - nature.com
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease

V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

Medicinal prospects of antioxidants: A review

K Neha, MR Haider, A Pathak, MS Yar - European journal of medicinal …, 2019 - Elsevier
Free radicals generated due to exposure of radiation, environmental pollutants and as by-
products of metabolised drugs. These free radicals are antagonized by molecules which are …

Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets

Z Zhang, L Zhao, X Zhou, X Meng, X Zhou - Frontiers in immunology, 2023 - frontiersin.org
Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …

Herbal medicine for cardiovascular diseases: efficacy, mechanisms, and safety

A Shaito, DTB Thuan, HT Phu, THD Nguyen… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing
prevalence. They remain the leading causes of morbidity and mortality worldwide. The use …

Endothelial cell metabolism

G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Oxidative stress-induced endothelial dysfunction in cardiovascular diseases

A Shaito, K Aramouni, R Assaf, A Parenti, A Orekhov… - 2022 - qspace.qu.edu.qa
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …

Healthful aging mediated by inhibition of oxidative stress

SF Vatner, J Zhang, M Oydanich, T Berkman… - Ageing Research …, 2020 - Elsevier
The progressive increase in lifespan over the past century carries with it some adversity
related to the accompanying burden of debilitating diseases prevalent in the older …

Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease

W Frąk, A Wojtasińska, W Lisińska, E Młynarska… - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are disorders associated with the heart and circulatory
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …

Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review

M Mbikay - Frontiers in pharmacology, 2012 - frontiersin.org
Moringa oleifera (M. oleifera) is an angiosperm plant, native of the Indian subcontinent,
where its various parts have been utilized throughout history as food and medicine. It is now …