Nesfatin-1 was discovered in 2006 and implicated in the regulation of food intake.
Subsequently, its widespread central and peripheral distribution gave rise to additional …

The ion channel TRPV1 is involved in a wide range of processes including nociception,
thermosensation and, more recently discovered, energy homeostasis. Tightly controlling …

Nowadays, high epidemic obesity-triggered hypertension and diabetes seriously damage
social public health. There is now a general consensus that the body's fat content exceeding …

Since its discovery in 2006 by Oh-I and colleagues, NUCB2/nesfatin-1 encoded by
nucleobindin-2 (NUCB2) has drawn sustained attention as reflected in over 500 …

Abstract Nesfatin-1, an 82-amino acid polypeptide derived from the precursor protein
nucleobindin-2 (NUCB2), was first discovered in 2006 in the rat hypothalamus. The effects …

Ghrelin was first identified as an endogenous ligand of the growth hormone secretagogue
receptor (GHSR) in 1999, with the function of stimulating the release of growth hormone …

Abstract NUCB2/nesfatin-1 is an anorexigenic peptide hormone first known for its effects on
energy homeostasis. More recently, a growing evidence suggests a role of NUCB2/nesfatin …

The upper gastrointestinal tract plays an important role in sensing the arrival, amount and
chemical composition of a meal. Ingestion of a meal triggers a number of sensory signals in …

Background The ability of the gut to detect nutrients is critical to the regulation of gut
hormone secretion, food intake, and postprandial blood glucose control. Ingested nutrients …

Nesfatin-1 was discovered as an anorexigenic peptide derived from proteolytic cleavage of
the prepropeptide, nucleobindin 2 (NUCB2). It is widely expressed in central as well as …