The brain infers our spatial orientation and properties of the world from ambiguous and
noisy sensory cues. Judging self-motion (heading) in the presence of independently moving …

We use visual image motion to judge the movement of objects, as well as our own
movements through the environment. Generally, image motion components caused by …

Multiple areas of macaque cortex are involved in visual motion processing, but their relative
functional roles remain unclear. The medial superior temporal (MST) area is typically divided …

Cortical area MSTd contains cells sensitive to the radial expansion and contraction motion
patterns experienced during forward and backward self-motion. We investigated the open …

Steering demands rapid responses to heading deviations and uses optic flow to redirect self-
movement toward the intended destination. We trained monkeys in a naturalistic steering …

Navigation relies on the neural processing of sensory cues about observer self-movement
and spatial location. Neurons in macaque dorsal medial superior temporal cortex (MSTd) …

Many complex behaviors rely on guidance from sensations. To perform these behaviors, the
motor system must decode information relevant to the task from the sensory system …

We presented optic flow and real movement heading stimuli while recording MSTd neuronal
activity. Monkeys were alternately engaged in three tasks: visual detection of optic flow …

Navigation in a static environment along straight paths without eye movements produces
radial optic flow fields. A singularity called the focus of expansion (FoE) specifies the …

Our goal is to understand the neural basis of functional impairment in aging and Alzheimer's
disease (AD) to be able to characterize clinically significant decline and assess therapeutic …