Adenosine deaminase inhibition

S Bagheri, AA Saboury, T Haertlé - International journal of biological …, 2019 - Elsevier
Adenosine deaminase is a critical enzyme in purine metabolism that regulates intra and
extracellular adenosine concentrations by converting it to inosine. Adenosine is an important …

Therapeutic potentials of A2B adenosine receptor ligands: current status and perspectives

B Chandrasekaran, S Samarneh… - Current …, 2019 - ingentaconnect.com
Background: Adenosine receptors (ARs) are classified as A1, A2A, A2B, and A3 subtypes
belong to the superfamily of G-protein coupled receptors (GPCRs). More than 40% of …

Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins

E Moreno, J Canet, E Gracia, C Lluís, J Mallol… - Frontiers in …, 2018 - frontiersin.org
Adenosine is an endogenous purine nucleoside that acts in all living systems as a
homeostatic network regulator through many pathways, which are adenosine receptor (AR) …

Alterations of the Gut Microbiota and Metabolomics Associated with the Different Growth Performances of Macrobrachium rosenbergii Families

X Lan, X Peng, T Du, Z **a, Q Gao, Q Tang, S Yi… - Animals, 2023 - mdpi.com
Simple Summary This study used 16S rRNA sequencing and metabolomic methods to
investigate the key gut microbiota and metabolites associated with the growth performance …

Tea for histamine anti-allergy: component analysis of tea extracts and potential mechanism for treating histamine anti-allergy

Z Huang, L Zhang, J Xuan, L Yang, T Zhao… - Frontiers in …, 2024 - frontiersin.org
In China, Camellia plants are widely used to reduce atopic dermatitis and inflammation-
related diseases, but their protective mechanisms remain unclear. This study investigated …

Adenosine: direct and indirect actions on gastric acid secretion

RM Arin, A Gorostidi, H Navarro-Imaz, Y Rueda… - Frontiers in …, 2017 - frontiersin.org
Composed by a molecule of adenine and a molecule of ribose, adenosine is a paradigm of
recyclable nucleoside with a multiplicity of functions that occupies a privileged position in the …

Lipopolysaccharide-induced expansion of histidine decarboxylase-expressing Ly6G+ myeloid cells identified by exploiting histidine decarboxylase BAC-GFP …

J Takai, H Ohtsu, A Sato, S Uemura, T Fujimura… - Scientific reports, 2019 - nature.com
Histamine is a biogenic amine that is chiefly produced in mast cells and basophils and elicits
an allergic response upon stimulation. Histidine decarboxylase (HDC) is a unique enzyme …

Azelastine a potent antihistamine agent, as hypolipidemic and modulator for aortic calcification in diabetic hyperlipidemic rats model

MM Elseweidy, GM Elnagar, MM Elsawy… - Archives of Physiology …, 2022 - Taylor & Francis
Aim Our study aimed to illustrate the effect of the antihistaminic drug azelastine on aortic
calcification in diabetic hyperlipidemic (DH) rats along with the underlying molecular …

[HTML][HTML] Adenosine receptors

F Ciruela, E Sotelo - Molecules, 2017 - mdpi.com
Nearly 90 years ago, Drury and Szent-Györgyi revealed that adenosine produced profound
hypotension and bradycardia, and it affected kidney function in mammals [1]. Since then, the …

[PDF][PDF] BEHAVIOR OF SERUM ADENOSINE DEAMINASE AND ITS ISOENZYMES IN PATIENTS WITH URTICARIA

I NICOLAE, L DINU, G COMAN, M CIORTEA… - revistasrd.ro
Urticaria is a complex inflammatory disease, with often unidentified causes and incompletely
elucidated etiopathogenic mechanisms. The purpose of the paper is to determine the serum …