Thrombosis in vasculitis: from pathogenesis to treatment

G Emmi, E Silvestri, D Squatrito, A Amedei, E Niccolai… - Thrombosis journal, 2015 - Springer
In recent years, the relationship between inflammation and thrombosis has been deeply
investigated and it is now clear that immune and coagulation systems are functionally …

Cardiac manifestations in Behcet's disease

S Demirelli, H Degirmenci, S Inci… - Intractable & rare diseases …, 2015 - jstage.jst.go.jp
Behcet's disease (BD) is a chronic inflammatory disorder, with vasculitis underlying the
pathophysiology of its multisystemic effects. Venous pathology and thrombotic complications …

Critical role of neutrophil extracellular traps (NETs) in patients with Behcet's disease

A Le Joncour, R Martos, S Loyau, N Lelay… - Annals of the rheumatic …, 2019 - Elsevier
Objectives Behçet's disease (BD) is a chronic systemic vasculitis. Thrombosis is a frequent
and life-threatening complication. The pathogenesis of BD is poorly understood and …

A20 haploinsufficiency (HA20): clinical phenotypes and disease course of patients with a newly recognised NF-kB-mediated autoinflammatory disease

FA Aeschlimann, ED Batu, SW Canna, E Go… - Annals of the rheumatic …, 2018 - Elsevier
Objectives The association between mutations in TNFAIP3, encoding the NF-kB regulatory
protein A20, and a new autoinflammatory disease has recently been recognised. This study …

An update on autoinflammatory diseases

F Ciccarelli, M De Martinis… - Current Medicinal …, 2014 - ingentaconnect.com
Autoinflammatory diseases area group of clinical conditions other than autoimmune
diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of …

Behçet's disease: is there geographical variation? A review far from the Silk Road

NM Leonardo, J McNeil - International Journal of …, 2015 - Wiley Online Library
Behcet's Disease (BD) is a systemic vasculitis characterized by the triad of recurrent mouth
and genital ulcers with eye involvement. To date there are no laboratory tests specific for the …

Infliximab therapy for intestinal, neurological, and vascular involvement in Behcet disease: efficacy, safety, and pharmacokinetics in a multicenter, prospective, open …

T Hibi, S Hirohata, H Kikuchi, U Tateishi, N Sato… - Medicine, 2016 - journals.lww.com
Behçet disease (BD) is a multisystem disease associated with a poor prognosis in cases of
gastrointestinal, neurological, or vascular involvement. We conducted a multicenter …

A novel mechanism for NETosis provides antimicrobial defense at the oral mucosa

T Mohanty, J Sjögren, F Kahn… - Blood, The Journal …, 2015 - ashpublications.org
Neutrophils are essential for host defense at the oral mucosa and neutropenia or functional
neutrophil defects lead to disordered oral homeostasis. We found that neutrophils from the …

[HTML][HTML] Adalimumab for the treatment of Japanese patients with intestinal Behçet's disease

S Tanida, N Inoue, K Kobayashi, M Naganuma… - Clinical …, 2015 - Elsevier
Background & Aims Behçet's disease is a chronic, relapsing inflammatory disease that can
involve the mouth, skin, eyes, genitals, and intestines. Active intestinal Behçet's disease can …

Biological Treatments in Behçet's Disease: Beyond Anti‐TNF Therapy

F Caso, L Costa, D Rigante… - Mediators of …, 2014 - Wiley Online Library
Behçet's disease (BD) is universally recognized as a multisystemic inflammatory disease of
unknown etiology with chronic course and unpredictable exacerbations: its clinical spectrum …