Objective: To evaluate the neuroprotective effect of the nootropic drugs, piracetam (PIR) and
vinpocetine (VIN), in rotenone-induced Parkinsonism in rats. Materials and Methods: Sixty …

Brain mesolimbic dopamine (DA) neurons are considered critical for the dependence-
producing action of nicotine, and its stimulatory effect on behavior and DA …

Buspirone, a partial agonist of 5-hydroxytryptamine1A autoreceptors, selectively blocks
presynaptic nigrostriatal D2 dopamine (DA) autoreceptors. At doses which antagonised …

EFFECTS OF BUSF’IRONE ON AN ANIMAL MODEL OF TARDIVE DYSKINESIA (Final form,
October 1999) Page 1 ELSEVIER Prog Neuro-PsychoPhamacoI & Bwl Psychiat 1999, Vol. ‘23 …

In the first experiment, separate groups of rats (n= 7) were treated with either saline, cocaine
(10 mg/kg), haloperidol (0.1 mg/kg), or cocaine (10 mg/kg) plus haloperidol (0.1 mg/kg) …

Animal models of obsessive-compulsive disorder (OCD) either may be induced in a
laboratory setting or may arise spontaneously in veterinary patients. Both models have their …

The effects of buspirone treatment on dopaminergic supersensitivity induced by long-term
haloperidol administration were studied; both spontaneous activity (locomotion and rearing …

According to the classical review by Sanberg et al.(1988), experimental catalepsy is defined
as “a failure of laboratory animals to correct an externally imposed posture”. Indeed, as …

Yawning behavior is an experimental tool to study physiological responses, to elucidate the
mechanissms of action of some drugs and hormones, and it is also a paradigm for some …

Previous studies have shown that rats withdrawn from long-term treatment with dopamine
receptor blockers exhibit dopaminergic supersensitivity, which can be behaviorally …