Targeting autophagy using natural compounds for cancer prevention and therapy
S Deng, MK Shanmugam, AP Kumar, CT Yap, G Sethi… - Cancer, 2019 - Wiley Online Library
Autophagy, also known as macroautophagy, is a tightly regulated process involved in the
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
An update on pharmacological potential of boswellic acids against chronic diseases
Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …
Pharmacology and pharmacokinetics of vitamin E: Nanoformulations to enhance bioavailability
Vitamin E belongs to the family of lipid-soluble vitamins and can be divided into two groups,
tocopherols and tocotrienols, with four isomers (alpha, beta, gamma and delta). Although …
tocopherols and tocotrienols, with four isomers (alpha, beta, gamma and delta). Although …
[HTML][HTML] Interplay of dietary antioxidants and gut microbiome in human health: What has been learnt thus far?
The human gastrointestinal tract harbors a diverse range of microbial species, which helps
to regulate various biological processes such as homeostasis of the gut barrier, stimulation …
to regulate various biological processes such as homeostasis of the gut barrier, stimulation …
Piceatannol: A natural stilbene for the prevention and treatment of cancer
Abstract The World Health Organization (WHO) has documented that cancer is the second
foremost reason for death worldwide. Various factors are responsible for cancer, for …
foremost reason for death worldwide. Various factors are responsible for cancer, for …
The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy
M Garg, MK Shanmugam, V Bhardwaj… - Medicinal research …, 2021 - Wiley Online Library
Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …
Vitamin E as an essential micronutrient for human health: Common, novel, and unexplored dietary sources
Vitamin E comprises a group of vitamers that includes tocopherols and tocotrienols. They
occur in four homologues according to the number and position of methyl groups attached to …
occur in four homologues according to the number and position of methyl groups attached to …
Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets
In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …
the mortality rate due to this widespread disease has increased drastically over the last few …
Potential of zerumbone as an anti-cancer agent
Cancer is still a major risk factor to public health globally, causing approximately 9.8 million
deaths worldwide in 2018. Despite advances in conventional treatment modalities for cancer …
deaths worldwide in 2018. Despite advances in conventional treatment modalities for cancer …
Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies
Z Zainal, H Khaza'ai, AK Radhakrishnan… - Food Research …, 2022 - Elsevier
Palm oil is rich in tocotrienols (T3s), a type of vitamin E that has garnered considerable
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …