Flavonoids as antiobesity agents: A review

AT Rufino, VM Costa, F Carvalho… - Medicinal Research …, 2021‏ - Wiley Online Library
Obesity is a global health problem that affects all age groups in both develo** and
developed countries. In recent years, the prevalence of overweight and obesity has reached …

[HTML][HTML] PPARs-orchestrated metabolic homeostasis in the adipose tissue

C Sun, S Mao, S Chen, W Zhang, C Liu - International journal of …, 2021‏ - mdpi.com
It has been more than three decades since peroxisome proliferator-activated receptors
(PPARs) were first discovered. Many investigations have revealed the central regulators of …

Dietary alpha‐ketoglutarate promotes beige adipogenesis and prevents obesity in middle‐aged mice

Q Tian, J Zhao, Q Yang, B Wang, JM Deavila… - Aging …, 2020‏ - Wiley Online Library
Aging usually involves the progressive development of certain illnesses, including diabetes
and obesity. Due to incapacity to form new white adipocytes, adipose expansion in aged …

The role of brown adipose tissue dysfunction in the development of cardiovascular disease

HJ Chen, T Meng, PJ Gao, CC Ruan - Frontiers in Endocrinology, 2021‏ - frontiersin.org
Brown adipose tissue (BAT), consisted of brown adipocytes and stromal vascular fraction,
which includes endothelial cells, lymphocytes, fibroblasts and stem cells, plays a vital role in …

[HTML][HTML] Thermogenic fat: development, physiological function, and therapeutic potential

BB Brandão, A Poojari, A Rabiee - International Journal of Molecular …, 2021‏ - mdpi.com
The concerning worldwide increase of obesity and chronic metabolic diseases, such as
T2D, dyslipidemia, and cardiovascular disease, motivates further investigations into …

Regulation of human brown adipose tissue by adenosine and A2A receptors – studies with [15O]H2O and [11C]TMSX PET/CT

M Lahesmaa, V Oikonen, S Helin, P Luoto… - European journal of …, 2019‏ - Springer
Purpose Brown adipose tissue (BAT) has emerged as a potential target to combat obesity
and diabetes, but novel strategies to activate BAT are needed. Adenosine and A 2A receptor …

[HTML][HTML] Brown and beige adipose tissue: New therapeutic targets for metabolic disorders

BS Magro, DPM Dias - Health Sciences Review, 2024‏ - Elsevier
Brown adipocytes constitute a specialized tissue in heat build-up (ie, thermogenesis) due to
their mitochondrial uncoupling capacity, as they express thermogenic genes, playing a role …

Impact of pesticide exposure on adipose tissue development and function

RM Gutgesell, EE Tsakiridis, S Jamshed… - Biochemical …, 2020‏ - portlandpress.com
Obesity is a leading cause of morbidity, mortality and health care expenditure whose
incidence is rapidly rising across the globe. Although the cause of the obesity epidemic is …

Molecular mechanisms of vaspin action–from adipose tissue to skin and bone, from blood vessels to the brain

J Weiner, K Zieger, J Pippel, JT Heiker - Protein Reviews–Purinergic …, 2019‏ - Springer
Visceral adipose tissue-derived serine protease inhibitor (vaspin) or SERPINA12 according
to the serpin nomenclature was identified together with other genes and gene products that …

[HTML][HTML] Cyanidin-3-O-β-glucoside regulates the activation and the secretion of adipokines from brown adipose tissue and alleviates diet induced fatty liver

L Pei, T Wan, S Wang, M Ye, Y Qiu, R Jiang… - Biomedicine & …, 2018‏ - Elsevier
Abstract Aim Cyanidin-3-O-β-glucoside (Cy-3-G) the most abundant monomer of
anthocyanins has multiple protective effects on many diseases. To date, whether Cy-3-G …