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Bacteria in cancer initiation, promotion and progression
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …
Microbiota in health and diseases
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …
since its discovery. Depending on the localized regions, microbiota can be classified into …
Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis
F Cao, L **, Y Gao, Y Ding, H Wen, Z Qian… - Nature …, 2023 - nature.com
Inflammatory bowel disease can be caused by the dysfunction of the intestinal mucosal
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …
A distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche
Fusobacterium nucleatum (Fn), a bacterium present in the human oral cavity and rarely
found in the lower gastrointestinal tract of healthy individuals, is enriched in human …
found in the lower gastrointestinal tract of healthy individuals, is enriched in human …
Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer
The tumour-associated microbiota is an intrinsic component of the tumour microenvironment
across human cancer types,. Intratumoral host–microbiota studies have so far largely relied …
across human cancer types,. Intratumoral host–microbiota studies have so far largely relied …
Fusobacterium nucleatum, a key pathogenic factor and microbial biomarker for colorectal cancer
N Wang, JY Fang - Trends in Microbiology, 2023 - cell.com
Colorectal cancer (CRC), one of the most prevalent cancers, has complex etiology. The
dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …
dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …
Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses
Increasing evidence implicates the tumor microbiota as a factor that can influence cancer
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …
Intratumoural microbiota: a new frontier in cancer development and therapy
Y Cao, H **a, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …
physiological and pathological processes. Some studies discovered that tumour tissues …
Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities
G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
Genetic and biological hallmarks of colorectal cancer
Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …
tumors, and these insights have illuminated early detection, risk stratification, prevention …