The emerging roles of circRNAs in cancer and oncology
Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …
non-coding RNA molecules, many of which have key roles in cancer development and …
The biogenesis, biology and characterization of circular RNAs
Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes
with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by …
with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by …
[HTML][HTML] Circular RNA-protein interactions: functions, mechanisms, and identification
Circular RNAs (circRNAs) are covalently closed, endogenous RNAs with no 5′ end caps or
3′ poly (A) tails. These RNAs are expressed in tissue-specific, cell-specific, and …
3′ poly (A) tails. These RNAs are expressed in tissue-specific, cell-specific, and …
Translation and functional roles of circular RNAs in human cancer
M Lei, G Zheng, Q Ning, J Zheng, D Dong - Molecular cancer, 2020 - Springer
Circular RNAs (circRNAs) are a new class of non-coding RNAs formed by covalently closed
loops through backsplicing. Recent methodologies have enabled in-depth characterization …
loops through backsplicing. Recent methodologies have enabled in-depth characterization …
A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma
JL Duan, W Chen, JJ **e, ML Zhang, RC Nie, H Liang… - Molecular cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) regulate various biological activities and
have been shown to play crucial roles in hepatocellular carcinoma (HCC) progression …
have been shown to play crucial roles in hepatocellular carcinoma (HCC) progression …
Characterizing extracellular vesicles and their diverse RNA contents
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …
Biogenesis and functions of circular RNAs come into focus
Many eukaryotic protein-coding genes are able to generate exonic circular RNAs. Most of
these covalently linked transcripts are expressed at low levels, but some accumulate to …
these covalently linked transcripts are expressed at low levels, but some accumulate to …
An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations
Parietal cortex RNA-sequencing (RNA-seq) data were generated from individuals with and
without Alzheimer disease (AD; n control= 13; n AD= 83) from the Knight Alzheimer Disease …
without Alzheimer disease (AD; n control= 13; n AD= 83) from the Knight Alzheimer Disease …
A 360 view of circular RNAs: From biogenesis to functions
JE Wilusz - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
The first circular RNA (circRNA) was identified more than 40 years ago, but it was only
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
Circular RNAs open a new chapter in cardiovascular biology
S Aufiero, YJ Reckman, YM Pinto… - Nature Reviews …, 2019 - nature.com
Circular RNAs (circRNAs) are emerging as a new class of non-coding RNA molecules. This
unusual class of RNA species is generated by a back-splicing event of one or two exons …
unusual class of RNA species is generated by a back-splicing event of one or two exons …