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Detection and analysis of chiral molecules as disease biomarkers
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
Guide to metabolomics analysis: a bioinformatics workflow
Y Chen, EM Li, LY Xu - Metabolites, 2022 - mdpi.com
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …
key purpose of metabolomics is to identify the metabolites corresponding to each biological …
Applications of machine learning in metabolomics: Disease modeling and classification
Metabolomics research has recently gained popularity because it enables the study of
biological traits at the biochemical level and, as a result, can directly reveal what occurs in a …
biological traits at the biochemical level and, as a result, can directly reveal what occurs in a …
Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?
Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …
develop and remain healthy. Most of these metabolites are produced by microbiota and …
Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis
Lung cancer is the leading cause of cancer mortality, and early detection is key to improving
survival. However, there are no reliable blood-based tests currently available for early-stage …
survival. However, there are no reliable blood-based tests currently available for early-stage …
[HTML][HTML] Metabolomics in the context of plant natural products research: From sample preparation to metabolite analysis
Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …
compounds for drug development. Natural extracts are usually composed of hundreds to …
Cancer metabolites: promising biomarkers for cancer liquid biopsy
Cancer exerts a multitude of effects on metabolism, including the reprogramming of cellular
metabolic pathways and alterations in metabolites that facilitate inappropriate proliferation of …
metabolic pathways and alterations in metabolites that facilitate inappropriate proliferation of …
Development of a plasma pseudotargeted metabolomics method based on ultra-high-performance liquid chromatography–mass spectrometry
F Zheng, X Zhao, Z Zeng, L Wang, W Lv, Q Wang… - Nature protocols, 2020 - nature.com
Untargeted methods are typically used in the detection and discovery of small organic
compounds in metabolomics research, and ultra-high-performance liquid chromatography …
compounds in metabolomics research, and ultra-high-performance liquid chromatography …
[HTML][HTML] Navigating challenges and opportunities in multi-omics integration for personalized healthcare
The field of multi-omics has witnessed unprecedented growth, converging multiple scientific
disciplines and technological advances. This surge is evidenced by a more than doubling in …
disciplines and technological advances. This surge is evidenced by a more than doubling in …