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A review of the botany, phytochemistry, traditional uses, pharmacology, toxicology, and quality control of the Astragalus memeranaceus
P Wang, Z Wang, Z Zhang, H Cao, L Kong… - Frontiers in …, 2023 - frontiersin.org
Astragali Radix (Huangqi) is mainly distributed in the Northern Hemisphere, South America,
and Africa and rarely in North America and Oceania. It has long been used as an …
and Africa and rarely in North America and Oceania. It has long been used as an …
Calycosin: a review of its pharmacological effects and application prospects
M Deng, H Chen, J Long, J Song, L **e… - Expert Review of Anti …, 2021 - Taylor & Francis
ABSTRACT Introduction: Calycosin (CA), a typical phytoestrogen extracted from root of
Astragalus membranaceus. On the basis of summarizing the pharmacological and …
Astragalus membranaceus. On the basis of summarizing the pharmacological and …
Calycosin reduces myocardial fibrosis and improves cardiac function in post-myocardial infarction mice by suppressing TGFBR1 signaling pathways
G Chen, H Xu, T Xu, W Ding, G Zhang, Y Hua, Y Wu… - Phytomedicine, 2022 - Elsevier
Background Excessive myocardial fibrosis is the pathological basis of heart failure following
myocardial infarction (MI). Although calycosin improves cardiac function, its effect on cardiac …
myocardial infarction (MI). Although calycosin improves cardiac function, its effect on cardiac …
Gut–liver axis derangement in non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is the most frequent type of chronic liver disease in
the pediatric age group, paralleling an obesity pandemic. A “multiple-hit” hypothesis has …
the pediatric age group, paralleling an obesity pandemic. A “multiple-hit” hypothesis has …
[HTML][HTML] Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR
Nuclear receptors (NRs) represent attractive targets for the treatment of metabolic syndrome-
related diseases. In addition, natural products are an interesting pool of potential ligands …
related diseases. In addition, natural products are an interesting pool of potential ligands …
Astragalus and its formulas as a therapeutic option for fibrotic diseases: Pharmacology and mechanisms
Y Zhu, Y Chai, G **ao, Y Liu, X **e, W **ao… - Frontiers in …, 2022 - frontiersin.org
Fibrosis is the abnormal deposition of extracellular matrix, characterized by accumulation of
collagen and other extracellular matrix components, which causes organ dysfunction and …
collagen and other extracellular matrix components, which causes organ dysfunction and …
Kinsenoside alleviates inflammation and fibrosis in experimental NASH mice by suppressing the NF-κB/NLRP3 signaling pathway
Y Deng, Q Xu, T Chen, J Ming, Y Wang, L Mao, J Zhou… - Phytomedicine, 2022 - Elsevier
Background Non-alcoholic steatohepatitis (NASH) has replaced viral hepatitis as the main
driver of the rising morbidity and mortality associated with cirrhosis and liver cancer …
driver of the rising morbidity and mortality associated with cirrhosis and liver cancer …
Baicalin attenuates non-alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, inflammation and fibrosis in mice
J Zhang, H Zhang, X Deng, N Zhang, B Liu, S **n, G Li… - Life sciences, 2018 - Elsevier
Aims Baicalin (BA), an active flavonoid compound originating from the herb of Scutellaria
baicalensis Georgi, has been previously shown to exert anti-inflammation and anti-oxidant …
baicalensis Georgi, has been previously shown to exert anti-inflammation and anti-oxidant …
The pathogenesis of HCC driven by NASH and the preventive and therapeutic effects of natural products
G Shao, Y Liu, L Lu, G Zhang, W Zhou, T Wu… - Frontiers in …, 2022 - frontiersin.org
Nonalcoholic steatohepatitis (NASH) is a clinical syndrome with pathological changes that
are similar to those of alcoholic hepatitis without a history of excessive alcohol consumption …
are similar to those of alcoholic hepatitis without a history of excessive alcohol consumption …
Hepatic fibrosis: targeting peroxisome proliferator-activated receptor alpha from mechanism to medicines
Liver fibrosis is the result of sustained chronic liver injury and inflammation leading to
hepatocyte cell death followed by the formation of fibrous scars, which is the hallmark of …
hepatocyte cell death followed by the formation of fibrous scars, which is the hallmark of …