Simple Summary Cutaneous squamous cell carcinoma (cSCC) is the second most common
form of skin cancer worldwide. Due to its high mutational burden, cSCC remains poorly …

Cutaneous squamous cell carcinoma (cSCC) is a disease with globally rising incidence and
poor prognosis for patients with advanced or metastatic disease. Epithelial-mesenchymal …

Metastatic prostate cancer is one of the leading causes of male cancer deaths in the western
world. Obesity significantly increases the risk of metastatic disease and is associated with a …

Metastatic cutaneous squamous cell carcinoma (CSCC) is a highly morbid disease requiring
radical surgery and adjuvant therapy, which is associated with a poor prognosis. Yet …

Simple Summary This study investigates the characteristics of metastatic cutaneous
squamous cell carcinoma (cSCC) to improve patient risk stratification. By comparing patients …

Background Cutaneous squamous cell carcinomas (cSCCs) are the second most common
human cancer and have been characterized by RNA sequencing (RNA-Seq); however, the …

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer.
While many treatments exist, our understanding of its genomic progression, especially from …

Simple Summary Cutaneous squamous cell carcinoma (cSCC) is a very common skin
cancer with poor prognosis for patients with advanced disease. PI3K/AKT/mTOR and cell …

The aberrant proteolytic landscape of the tumor microenvironment is a key contributor of
cancer progression. Overexpression of urokinase plasminogen activator (uPA) and/or its …

Simple Summary Many solid tumours, such as those of the breast, colon, and prostate, have
well established molecular markers of malignancy. However, in certain cancers, such as …