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Periplasmic chaperones: outer membrane biogenesis and envelope stress
Envelope biogenesis and homeostasis in gram-negative bacteria are exceptionally intricate
processes that require a multitude of periplasmic chaperones to ensure cellular survival …
processes that require a multitude of periplasmic chaperones to ensure cellular survival …
Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model
Gram-negative bacteria have a double-membrane cellular envelope that enables them to
colonize harsh environments and prevents the entry of many clinically available antibiotics …
colonize harsh environments and prevents the entry of many clinically available antibiotics …
Outer membrane protein assembly mediated by BAM-SurA complexes
The outer membrane is a formidable barrier that protects Gram-negative bacteria against
environmental threats. Its integrity requires the correct folding and insertion of outer …
environmental threats. Its integrity requires the correct folding and insertion of outer …
The bacterial cell envelope
TJ Silhavy, D Kahne, S Walker - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
The bacteria cell envelope is a complex multilayered structure that serves to protect these
organisms from their unpredictable and often hostile environment. The cell envelopes of …
organisms from their unpredictable and often hostile environment. The cell envelopes of …
Outer membrane biogenesis
A Konovalova, DE Kahne… - Annual review of …, 2017 - annualreviews.org
The hallmark of gram-negative bacteria and organelles such as mitochondria and
chloroplasts is the presence of an outer membrane. In bacteria such as Escherichia coli, the …
chloroplasts is the presence of an outer membrane. In bacteria such as Escherichia coli, the …
Outer membrane protein biogenesis in Gram-negative bacteria
SE Rollauer, MA Sooreshjani… - … Transactions of the …, 2015 - royalsocietypublishing.org
Gram-negative bacteria contain a double membrane which serves for both protection and for
providing nutrients for viability. The outermost of these membranes is called the outer …
providing nutrients for viability. The outermost of these membranes is called the outer …
Assembly and maintenance of lipids at the bacterial outer membrane
E Lundstedt, D Kahne, N Ruiz - Chemical reviews, 2020 - ACS Publications
The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …
environments and provides intrinsic resistance to many antibiotics. This membrane is …
β-Barrel membrane protein assembly by the Bam complex
CL Hagan, TJ Silhavy, D Kahne - Annual review of biochemistry, 2011 - annualreviews.org
β-barrel membrane proteins perform important functions in the outer membranes (OMs) of
Gram-negative bacteria and of the mitochondria and chloroplasts of eukaryotes. The protein …
Gram-negative bacteria and of the mitochondria and chloroplasts of eukaryotes. The protein …
Reconstitution of outer membrane protein assembly from purified components
CL Hagan, S Kim, D Kahne - Science, 2010 - science.org
β-barrel membrane proteins in Gram-negative bacteria, mitochondria, and chloroplasts are
assembled by highly conserved multi-protein complexes. The mechanism by which these …
assembled by highly conserved multi-protein complexes. The mechanism by which these …
Microbial Peptidyl-Prolyl cis/trans Isomerases (PPIases): Virulence Factors and Potential Alternative Drug Targets
Initially discovered in the context of immunomodulation, peptidyl-prolyl cis/trans isomerases
(PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at …
(PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at …