Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release
DB Zorov, M Juhaszova, SJ Sollott - Physiological reviews, 2014 - journals.physiology.org
Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of
potentially damaging levels of reactive oxygen species (ROS), Ca2+, etc., which must be …
potentially damaging levels of reactive oxygen species (ROS), Ca2+, etc., which must be …
Catalysis and Electron Transfer in De Novo Designed Metalloproteins
One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …
in our ability to design new, non-native, catalytically active protein scaffolds. This review …
Structure and function of haemoglobins
DA Gell - Blood Cells, Molecules, and Diseases, 2018 - Elsevier
Haemoglobin (Hb) is widely known as the iron-containing protein in blood that is essential
for O 2 transport in mammals. Less widely recognised is that erythrocyte Hb belongs to a …
for O 2 transport in mammals. Less widely recognised is that erythrocyte Hb belongs to a …
How biology handles nitrite
Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action
A Lawen, DJR Lane - Antioxidants & redox signaling, 2013 - liebertpub.com
Iron is a crucial factor for life. However, it also has the potential to cause the formation of
noxious free radicals. These double-edged sword characteristics demand a tight regulation …
noxious free radicals. These double-edged sword characteristics demand a tight regulation …
Handling heme: The mechanisms underlying the movement of heme within and between cells
Heme is an essential cofactor and signaling molecule required for virtually all aerobic life.
However, excess heme is cytotoxic. Therefore, heme must be safely transported and …
However, excess heme is cytotoxic. Therefore, heme must be safely transported and …
Heme uptake and utilization by gram-negative bacterial pathogens
KL Richard, BR Kelley, JG Johnson - Frontiers in cellular and …, 2019 - frontiersin.org
Iron is a transition metal utilized by nearly all forms of life for essential cellular processes,
such as DNA synthesis and cellular respiration. During infection by bacterial pathogens, the …
such as DNA synthesis and cellular respiration. During infection by bacterial pathogens, the …
Harnessing the power of enzymes for environmental stewardship
Enzymes are versatile catalysts with a growing number of applications in biotechnology.
Their properties render them also attractive for waste/pollutant treatment processes and their …
Their properties render them also attractive for waste/pollutant treatment processes and their …
Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system
During the past 5 decades, it has been widely promulgated that the chemicals in plants that
are good for health act as direct scavengers of free radicals. Here we review evidence that …
are good for health act as direct scavengers of free radicals. Here we review evidence that …
Non-symbiotic haemoglobins—what's happening beyond nitric oxide scavenging?
RD Hill - AoB plants, 2012 - academic.oup.com
Background and aims Non-symbiotic haemoglobins have been an active research topic for
over 30 years, during which time a considerable portfolio of knowledge has accumulated …
over 30 years, during which time a considerable portfolio of knowledge has accumulated …