The study of autoimmunity mediated by immunoglobulin E (IgE) autoantibodies, which may
be termed autoallergy, is in its infancy. It is now recognized that systemic lupus …

Tumors are highly complex and heterogenous ecosystems where malignant cells interact
with healthy cells and the surrounding extracellular matrix (ECM). Solid tumors contain large …

Contenido de gran interés para residentes y dermatólogos en práctica que se ha convertido
en una referencia obligatoria de la especialidad para la comprensión, el diagnóstico y el …

Epidermolysis bullosa (EB), a group of heritable skin fragility disorders, is characterized by
blistering, erosions and chronic ulcers in the skin and mucous membranes. In some forms …

Abstract UL16-binding proteins (ULBPs) belong to a family of ligands for NKG2D activating
receptor of human natural killer (NK) cells. We previously reported that RAET1E2, a soluble …

Pemphigoid diseases (including bullous pemphigoid, mucous membrane pemphigoid,
pemphigoid gestationis, linear IgA dermatosis, lichen planus pemphigoides, and anti-p200 …

Background Diagnosis and curative treatment of cholangiocarcinoma (CC) often comes too
late due to the lack of reliable tumour markers especially in patients with primary sclerosing …

Type XVII collagen (COL 17) is a transmembranous protein that is mainly expressed in the
epidermal basal keratinocytes. Epidermal‐dermal attachment requires COL 17 expression …

BP180 is a type II collagenous transmembrane protein and is best known as the major
autoantigen in the blistering skin disease bullous pemphigoid (BP). The BP180 trimer is a …

Macrophages exhibit a phenotypic plasticity that enables them to orchestrate specific
immune responses to distinct threats. The microbial product lipopolysaccharide (LPS) and …