The transporter associated with antigen processing (TAP) is an ATP-binding cassette (ABC)
transporter essential to cellular immunity against viral infection. Some persistent viruses …

Living matter is defined by metastability, implying a tightly balanced synthesis and turnover
of cellular components. The first step of eukaryotic protein degradation via the ubiquitin …

ABC transporters form one of the largest protein superfamilies in all domains of life,
catalyzing the movement of diverse substrates across membranes. In this key position, ABC …

Antigen presentation is a key process of the immune system and is responsible for the
activation of T cells. The main characters are the major histocompatibility complex class I …

Antigen presentation via major histocompatibility complex class I (MHC-I) molecules is
essential for surveillance by the adaptive immune system. Central to this process is the …

Japanese flounder (Paralichthys olivaceus) is one of the most economically important
marine fish cultured in north Asia. Vibrio anguillarum is a severe bacterial pathogen to …

Salt bridges in lipid bilayers play a decisive role in the dynamic assembly and downstream
signaling of the natural killer and T-cell receptors. Here, we describe the identification of an …

Background: Predicting protein-peptide binding affinity is one of the leading research
subjects in peptide drug design and repositioning. In previous studies, models constructed …

Live‐cell labeling, super‐resolution microscopy, single‐molecule applications, protein
localization, or chemically induced assembly are emerging approaches, which require …