Vascular endothelial cells (ECs) form a semiselective barrier for macromolecules and cell
elements regulated by dynamic interactions between cytoskeletal elements and cell …

Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for develo** psychiatric and behavioral disorders later in life …

An epigenetic profile defining the DNA methylation age (DNA m age) of an individual has
been suggested to be a biomarker of aging, and thus possibly providing a tool for …

Modern lifestyle, genetics, nutritional overload through high-fat diet attributed prevalence
and diabetes outcomes with various complications primarily due to obesity in which energy …

Obesity is associated with increased classically activated M1 adipose tissue macrophages
(ATMs) and decreased alternatively activated M2 ATMs, both of which contribute to obesity …

Background—The epigenome refers to marks on the genome, including DNA methylation
and histone modifications, that regulate the expression of underlying genes. A consistent …

Several types of epigenetic marks facilitate the complex patterning required for normal
human development. These epigenetic marks include DNA methylation at CpG …

Adipose tissue macrophages (ATMs) undergo a phenotypic switch from alternatively
activated antiinflammatory M2 macrophages in lean individuals to classically activated …

variation of sequence elements present in the genome. An immediate question that surfaced
was how one single genome can give rise to all the different cell types of the human body …

Developmental speech and language disorders cover a wide range of childhood conditions
with overlap** but heterogeneous phenotypes and underlying etiologies. This …