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Quantifying and controlling bond multivalency for advanced nanoparticle targeting to cells
EY Makhani, A Zhang, JB Haun - Nano Convergence, 2021 - Springer
Nanoparticles have drawn intense interest as delivery agents for diagnosing and treating
various cancers. Much of the early success was driven by passive targeting mechanisms …
various cancers. Much of the early success was driven by passive targeting mechanisms …
Multiscale modeling of protein membrane interactions for nanoparticle targeting in drug delivery
Highlights•Computational methods for modeling hydrodynamic factors in nanoparticle
membrane interactions in targeted drug delivery.•Computational frameworks for predicting …
membrane interactions in targeted drug delivery.•Computational frameworks for predicting …
Nondestructively Assemble Cell Membrane-Coated Nanoparticles by Host–Guest Interactions for Efficient Capture of Bioactive Compounds
Q Hu, Z Wang, J Li, W Cao, P Li, X **e… - Analytical …, 2024 - ACS Publications
Cell membrane-coated nanoparticles (CNPs) have emerged as an attractive nanomedical
tool. The basic premise is that the surface properties of natural cells can be integrated with …
tool. The basic premise is that the surface properties of natural cells can be integrated with …
The Quantity of Ligand-Receptor Interactions between Nanoparticles and Target Cells
K Schorr, S Beck, O Zimmer, FJ Baumann… - Nanoscale …, 2025 - pubs.rsc.org
Achieving high target cell avidity in combination with cell selectivity are fundamental, but
largely unachieved goals in the development of biomedical nanoparticle systems, which are …
largely unachieved goals in the development of biomedical nanoparticle systems, which are …
Adhesion dynamics of functionalized nanocarriers to endothelial cells: a dissipative particle dynamics study
Targeted drug delivery to endothelial cells utilizing functionalized nanocarriers (NCs) is an
essential procedure in therapeutic and diagnosis therapies. Using dissipative particle …
essential procedure in therapeutic and diagnosis therapies. Using dissipative particle …
Nanoparticles in bodily tissues: predicting their equilibrium distributions
Nanoparticles (NPs) interact within organisms via various biochemical interactions which
can bring benefits to society. Classically, fate/distribution of substances is assessed via …
can bring benefits to society. Classically, fate/distribution of substances is assessed via …
Systemically applicable glutamine-functionalized polymer exerting multivalent interaction with tumors overexpressing ASCT2
Y Honda, T Nomoto, H Takemoto, M Matsui… - ACS Applied Bio …, 2021 - ACS Publications
Transporter ASCT2, which predominantly imports glutamine (Gln), is overexpressed in a
variety of cancer cells, and targeting ASCT2 is expected to be a promising approach for …
variety of cancer cells, and targeting ASCT2 is expected to be a promising approach for …
Biophysical considerations in the rational design and cellular targeting of flexible polymeric nanoparticles
How nanoparticle (NP) mechanical properties impact multivalent ligand–receptor‐mediated
binding to cell surfaces, the avidity, propensity for internalization, and effects due to …
binding to cell surfaces, the avidity, propensity for internalization, and effects due to …
Computational Study of Near Wall Dynamics and Adhesion of Functionalized Nanocarriers to Endothelial Cells
S Akbarishandiz - 2024 - search.proquest.com
This dissertation delves into a comprehensive computational investigation of the intricate
behavior of macromolecules at both the liquid/liquid and solid/liquid interfaces. By …
behavior of macromolecules at both the liquid/liquid and solid/liquid interfaces. By …
Entropic Pressure on a Biological Vesicle with Surface Tension
R Hassan, M Cai, ATN Vo, S Farokhirad, X Yan… - Available at SSRN … - papers.ssrn.com
Entropic forces play a critical role in the dynamics and stability of soft matter systems, par-
ticularly in biological membranes and vesicles. The origin of these forces lies in the …
ticularly in biological membranes and vesicles. The origin of these forces lies in the …