Pathological and therapeutic roles of bioactive peptide trefoil factor 3 in diverse diseases: recent progress and perspective
Y Yang, Z Lin, Q Lin, W Bei, J Guo - Cell death & disease, 2022 - nature.com
Abstract Trefoil factor 3 (TFF3) is the last small-molecule peptide found in the trefoil factor
family, which is mainly secreted by intestinal goblet cells and exerts mucosal repair effect in …
family, which is mainly secreted by intestinal goblet cells and exerts mucosal repair effect in …
Neo-vascularization-based therapeutic perspectives in advanced ovarian cancer
The process of angiogenesis is well described for its potential role in the development of
normal ovaries, and physiological functions as well as in the initiation, progression, and …
normal ovaries, and physiological functions as well as in the initiation, progression, and …
Enhanced isolation and release of circulating tumor cells using nanoparticle binding and ligand exchange in a microfluidic chip
The detection of rare circulating tumor cells (CTCs) in the blood of cancer patients has the
potential to be a powerful and noninvasive method for examining metastasis, evaluating …
potential to be a powerful and noninvasive method for examining metastasis, evaluating …
Delivery of miR-200c-3p using tumor-targeted mesoporous silica nanoparticles for breast cancer therapy
I Garrido-Cano, A Adam-Artigues… - … Applied Materials & …, 2023 - ACS Publications
Despite advances in breast cancer treatment, it remains the leading cause of cancer-related
death in women worldwide. In this context, microRNAs have emerged as potential …
death in women worldwide. In this context, microRNAs have emerged as potential …
Subtype-GAN: a deep learning approach for integrative cancer subty** of multi-omics data
Motivation The discovery of cancer subty** can help explore cancer pathogenesis,
determine clinical actionability in treatment, and improve patients' survival rates. However …
determine clinical actionability in treatment, and improve patients' survival rates. However …
TFF3 drives Hippo dependent EGFR-TKI resistance in lung adenocarcinoma
Intrinsic and acquired resistance represent major obstacles to optimize outcomes in
epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) targeted therapy in …
epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) targeted therapy in …
TFF3 and TFF1 expression levels are elevated in colorectal cancer and promote the malignant behavior of colon cancer by activating the EMT process
A Yusufu, P Shayimu, R Tuerdi… - International …, 2019 - spandidos-publications.com
Reports on the roles of the secreted trefoil factor (TFF) 1 and 3 in colorectal cancer (CRC)
and their underlying mechanisms of action in tumorigenesis are not common and are …
and their underlying mechanisms of action in tumorigenesis are not common and are …
Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression
F Cheng, X Wang, YS Chiou, C He, H Guo… - Cell death & …, 2022 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer-related mortality with
a dismal prognosis that has changed little over the past few decades. Further understanding …
a dismal prognosis that has changed little over the past few decades. Further understanding …
Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation
V Pandey, B Wang, CD Mohan… - Proceedings of the …, 2018 - National Acad Sciences
Human BCL-2–associated death promoter (hBAD) is an apoptosis-regulatory protein
mediating survival signals to carcinoma cells upon phosphorylation of Ser99, among other …
mediating survival signals to carcinoma cells upon phosphorylation of Ser99, among other …
[HTML][HTML] TFF3 contributes to epithelial-mesenchymal transition (EMT) in papillary thyroid carcinoma cells via the MAPK/ERK signaling pathway
X Lin, H Zhang, J Dai, W Zhang, J Zhang, G Xue… - Journal of …, 2018 - ncbi.nlm.nih.gov
Trefoil factor 3 (TFF3) was found to be overexpressed in many types of tumours. Evidence
has shown that TFF3 plays an important role in tumour proliferation, migration and invasion …
has shown that TFF3 plays an important role in tumour proliferation, migration and invasion …