PTH is a major systemic regulator of the concentrations of calcium, phosphate, and active
vitamin D metabolites in blood and of cellular activity in bone. Intermittently administered …

The complementary DNA encoding a 585-amino acid parathyroid hormone-parathyroid
hormone-related peptide (PTH-PTHrP) receptor with seven potential membrane-spanning …

The parathyroid hormone-related peptide (PTHrP) gene was disrupted in murine embryonic
stem cells by homologous recombination, and the null allele was introduced into the mouse …

Parathyroid hormone (PTH), a major regulator of mineral ion metabolism, and PTH-related
peptide (PTHrP), which causes hypercalcemia in some cancer patients, stimulate multiple …

The regulatory role of parathyroid hormone (PTH)/PTH-related peptide (PTHrP) signaling
has been implicated in embryonic skeletal development. Here, we studied chondrogenic …

In the growth plate of endochondral bones, parathyroid hormone (PTH)-related peptide
(PTHrP) regulates the rate of chondrocyte maturation from prehypertrophic chondrocytes to …

Parathyroid hormone–related peptide (PTHrP) appears to play a major role in skeletal
development. Targeted disruption of the PTHrP gene in mice causes skeletal dysplasia with …

Abstract purpose: To determine the efficacy, dose-response relationship, and safety of 30,
60, and 90 mg of a single intravenous dose of an aminobisphosphonate, pamidronate …

Exposure of mammalian cells to UV irradiation induces rapid and transient expression of
early growth response-1 gene (Egr-1) encoding a transcription factor that plays a role in cell …

We have examined cell coupling and expression of gap junction proteins in monolayer
cultures of cells derived from human bone marrow stromal cells (BMC) and trabecular bone …