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MRI to differentiate multiple sclerosis, neuromyelitis optica, and myelin oligodendrocyte glycoprotein antibody disease
E Carnero Contentti, DT Okuda, JI Rojas… - Journal of …, 2023 - Wiley Online Library
Differentiating multiple sclerosis (MS) from other relapsing inflammatory autoimmune
diseases of the central nervous system such as neuromyelitis optica spectrum disorder …
diseases of the central nervous system such as neuromyelitis optica spectrum disorder …
[HTML][HTML] Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues
The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to
misdiagnosis, which remains an issue in present-day clinical practice. In addition …
misdiagnosis, which remains an issue in present-day clinical practice. In addition …
Diagnostic performance of cortical lesions and the central vein sign in multiple sclerosis
A Cagol, R Cortese, M Barakovic, S Schaedelin… - JAMA …, 2024 - jamanetwork.com
Importance Multiple sclerosis (MS) misdiagnosis remains an important issue in clinical
practice. Objective To quantify the performance of cortical lesions (CLs) and central vein …
practice. Objective To quantify the performance of cortical lesions (CLs) and central vein …
Disentangling the heterogeneity of multiple sclerosis through identification of independent neuropathological dimensions
A de Boer, AMR van den Bosch, NJ Mekkes… - Acta …, 2024 - Springer
Multiple sclerosis (MS) is a heterogeneous neurological disorder with regards to clinical
presentation and pathophysiology. Here, we investigated the heterogeneity of MS by …
presentation and pathophysiology. Here, we investigated the heterogeneity of MS by …
A novel imaging marker of cortical “cellularity” in multiple sclerosis patients
Pathological data showed focal inflammation and regions of diffuse neuronal loss in the
cortex of people with multiple sclerosis (MS). In this work, we applied a novel model (“soma …
cortex of people with multiple sclerosis (MS). In this work, we applied a novel model (“soma …
Time is myelin: early cortical myelin repair prevents atrophy and clinical progression in multiple sclerosis
Cortical myelin loss and repair in multiple sclerosis (MS) have been explored in
neuropathological studies, but the impact of these processes on neurodegeneration and the …
neuropathological studies, but the impact of these processes on neurodegeneration and the …
[HTML][HTML] From pathology to MRI and back: Clinically relevant biomarkers of multiple sclerosis lesions
Focal lesions in both white and gray matter are characteristic of multiple sclerosis (MS).
Histopathological studies have helped define the main underlying pathological processes …
Histopathological studies have helped define the main underlying pathological processes …
Intrinsic and extrinsic contributors to subregional thalamic volume loss in multiple sclerosis
EA Krijnen, E Salim Karam, AW Russo… - Annals of Clinical …, 2024 - Wiley Online Library
Objective To evaluate the intrinsic and extrinsic microstructural factors contributing to
atrophy within individual thalamic subregions in multiple sclerosis using in vivo high …
atrophy within individual thalamic subregions in multiple sclerosis using in vivo high …
Neuroimaging markers and disability scales in multiple sclerosis: A systematic review and meta-analysis
Background Multiple sclerosis (MS) is a central nervous system disorder marked by
progressive neurological impairments. Magnetic resonance imaging (MRI) parameters are …
progressive neurological impairments. Magnetic resonance imaging (MRI) parameters are …
Highly sensitive 3-Tesla real inversion recovery MRI detects leptomeningeal contrast enhancement in chronic active multiple sclerosis
Background Leptomeningeal contrast enhancement (LME) on T2-weighted Fluid-Attenuated
Inversion Recovery (T2-FLAIR) MRI is a reported marker of leptomeningeal inflammation …
Inversion Recovery (T2-FLAIR) MRI is a reported marker of leptomeningeal inflammation …