Metabolic syndrome is a global public health problem and predisposes individuals to
obesity, diabetes and cardiovascular disease. Although the underlying mechanisms remain …

Each follicle represents the basic functional unit of the ovary. From its very initial stage of
development, the follicle consists of an oocyte surrounded by somatic cells. The oocyte …

It is well known that adipokines are endocrine factors that are mainly secreted by white
adipose tissue. Their central role in energy metabolism is currently accepted. More recently …

In recent decades, the worldwide prevalence of obesity has risen dramatically and is
currently estimated to be around 20%. Obesity is linked to an increased risk of comorbidities …

Chemerin, a chemoattractant protein and adipokine, has been identified as the endogenous
ligand for a G protein–coupled receptor encoded by the gene CMKLR1 (also known as …

Often associated with obesity, male infertility represents a widespread condition that
challenges the wellbeing of the couple. In this article, we provide a comprehensive and …

Chemerin is a small chemotactic protein originally identified as the natural ligand of
CMKLR1. More recently, two other receptors, GPR1 and CCRL2, have been reported to bind …

Albeit essential for perpetuation of species, reproduction is an energy-demanding function
that can be adjusted to body metabolic status. Reproductive maturation and function can be …

Chemerin is a novel adipokine that plays a major role in adipogenesis and lipid metabolism.
It also induces inflammation and affects insulin signaling, steroidogenesis and …

Chlorpyrifos is a pesticide frequently detected in food and has been reported to disturb
endocrine and gut health, which was regulated by gut microbiota and enteroendocrine cells …