Research on the discovery and characterization of small, regulatory RNAs in bacteria has
exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …

Bacteria constitute a large and diverse class of infectious agents, causing devastating
diseases in humans, animals, and plants. Our understanding of gene expression control …

The stringent response is a conserved bacterial stress response mechanism that allows
bacteria to respond to nutritional challenges. It is mediated by the alarmones pppGpp and …

The intergenic regions in bacterial genomes can contain regulatory leader sequences and
small RNAs (sRNAs), which both serve to modulate gene expression. Computational …

Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …

It is now well established that small RNAs (sRNAs) have diverse and widespread roles in
regulating gene expression in all organisms (1–4). Mechanisms of action are varied but can …

6S RNA is a small, noncoding RNA that interacts with the primary holoenzyme form of RNA
polymerase. Escherichia coli 6S RNA is a global regulator that downregulates transcription …

The past decade has seen an explosion in discovery of small, non‐coding RNAs in all
organisms. As functions for many of the small RNAs have been identified, it has become …

Abstract 6S RNAs function through interaction with housekee** forms of RNA polymerase
holoenzyme (Eσ70 in Escherichia coli, EσA in Bacillus subtilis). Escherichia coli 6S RNA …

Small RNAs, a large class of ancient posttranscriptional regulators, have recently attracted
considerable attention. A plethora of small RNAs has been identified and characterized …