The genus Trichoderma contains fungi with high relevance for humans, with applications in
enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a …

IKAROS is a master regulator of cell fate determination in lymphoid and other hematopoietic
cells. This transcription factor orchestrates the association of epigenetic regulators with …

Coordinated activity-induced transcriptional changes across multiple neuron subtypes of the
prefrontal cortex (PFC) play a pivotal role in encoding and regulating major cognitive …

The tumor suppressor BAP1 interacts with chromatin-associated proteins and regulates cell
proliferation, but its mechanism of action and regulation remain poorly defined. We show …

Extracellular vesicles (EVs) are released by cells to the extracellular environment to mediate
inter-cellular communication. Proteins, lipids, nucleic acids and metabolites shuttled in these …

The deubiquitinase (DUB) and tumor suppressor BAP1 catalyzes ubiquitin removal from
histone H2A Lys-119 and coordinates cell proliferation, but how BAP1 partners modulate its …

Background The AD etiology is yet not properly known. Interactions among environmental
factors, multiple susceptibility genes and aging, contribute to AD. This study investigates the …

One of the most efficient plant resistance reactions to pathogen attack is the hypersensitive
response, a form of programmed cell death at infection sites. The Arabidopsis transcription …

The ubiquitin-mediated degradation system is responsible for controlling various tumor-
promoting processes, including DNA repair, cell cycle arrest, cell proliferation, apoptosis …

More than half a century ago, zinc was established as an essential micronutrient for normal
human physiology. In silico data suggest that about 10% of the human proteome potentially …