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Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and …
S Sankaran, MD George, E Reay, M Guadalupe… - Journal of …, 2008 - journals.asm.org
Gut-associated lymphoid tissue (GALT) is an early target for human immunodeficiency virus
type 1 (HIV-1) infection and is a site for severe CD4+ T-cell depletion. HIV-associated …
type 1 (HIV-1) infection and is a site for severe CD4+ T-cell depletion. HIV-associated …
Use of predictive markers of HIV disease progression in vaccine trials
S Gurunathan, R El Habib, L Baglyos, C Meric… - Vaccine, 2009 - Elsevier
Generating broadly neutralizing antibodies with candidate vaccines has remained an
elusive goal. Consequently, vaccine candidates developed have aimed at eliciting cell …
elusive goal. Consequently, vaccine candidates developed have aimed at eliciting cell …
The relation between symptoms, viral load, and viral load set point in primary HIV infection
Objectives: To examine the relation between symptoms, initial viral load, and viral load set
point in primary HIV infection (PHI). Design: Prospective cohort of patients with …
point in primary HIV infection (PHI). Design: Prospective cohort of patients with …
[HTML][HTML] HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life
Prevention of HIV-1 transmission at mucosal surfaces will likely require durable pre-existing
mucosal anti-HIV-1 antibodies (Abs). Defining the ontogeny, specificities and potentially …
mucosal anti-HIV-1 antibodies (Abs). Defining the ontogeny, specificities and potentially …
In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth
The broadly neutralizing human monoclonal antibodies (MAbs) 2F5 and 4E10, both
targeting the highly conserved human immunodeficiency virus type 1 (HIV-1) envelope …
targeting the highly conserved human immunodeficiency virus type 1 (HIV-1) envelope …
In-house HIV-1 RNA real-time RT-PCR assays: principle, available tests and usefulness in develo** countries
F Rouet, H Ménan, J Viljoen… - Expert review of …, 2008 - Taylor & Francis
The principle of currently available licensed HIV-1 RNA assays is based on real-time
technologies that continuously monitor the fluorescence emitted by the amplification …
technologies that continuously monitor the fluorescence emitted by the amplification …
HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the “test-and-treat” approach to reduce HIV transmission
The first aim of the study is to assess the distribution of HIV-1 RNA levels in subtype C
infection. Among 4,348 drug-naïve HIV-positive individuals participating in clinical studies in …
infection. Among 4,348 drug-naïve HIV-positive individuals participating in clinical studies in …
Early initiation of highly active antiretroviral therapy fails to reverse immunovirological abnormalities in gut-associated lymphoid tissue induced by acute HIV infection
C Tincati, M Biasin, A Bandera, M Violin… - Antiviral …, 2009 - journals.sagepub.com
Background During the acute phase of HIV infection, large CD4+ T-cell depletion occurs in
the gastrointestinal tract. The kinetics of CD4+ T-cell decrease and highly active …
the gastrointestinal tract. The kinetics of CD4+ T-cell decrease and highly active …
Modeling within-host evolution of HIV: mutation, competition and strain replacement
Virus evolution during infection of a single individual is a well-known feature of disease
progression in chronic viral diseases. However, the simplest models of virus competition for …
progression in chronic viral diseases. However, the simplest models of virus competition for …
Evolution of antibody responses in HIV-1 CRF01_AE acute infection: founder envelope V1V2 impacts the timing and magnitude of autologous neutralizing antibodies
S Kuriakose Gift, L Wieczorek, E Sanders-Buell… - Journal of …, 2023 - journals.asm.org
Understanding the dynamics of early immune responses to HIV-1 infection, including the
evolution of initial neutralizing and antibody-dependent cellular cytotoxicity (ADCC) …
evolution of initial neutralizing and antibody-dependent cellular cytotoxicity (ADCC) …