The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …

Chitosan-based nanomaterials have attracted significant attention in the biomedical field
because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature …

The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

New polymers are continuously developed for new therapeutic applications. New and
modified polymer chemistries that offer distinctive degradation and drug delivery are being …

The development of advanced nanomaterials and technologies is essential in biomedical
engineering to improve the quality of life. Chitosan-based nanomaterials are on the forefront …

Despite the increasing global incidence of brain disorders, achieving sufficient delivery
towards the central nervous system (CNS) remains a formidable challenge in terms of …

Currently, Alzheimer's disease (AD) accounts for more than half of all dementia cases.
Although genetics, age, and environmental factors affect the disease, the cause of AD is not …

Epilepsy is the fourth most common global neurological problem, which can be considered a
spectrum disorder because of its various causes, seizure types, its ability to vary in severity …

The rising significance of the field of biopolymers has driven the rapid progress of this
distinctive class of polymeric materials in the past decades. Biodegradable polymers have …

Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND)
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …