Not your father's planarian: a classic model enters the era of functional genomics

PA Newmark, AS Alvarado - Nature Reviews Genetics, 2002 - nature.com
Freshwater planarians were a classic model for studying the problems of development and
regeneration. However, as attention shifted towards animals with more rigid developmental …

Aging and longevity in the simplest animals and the quest for immortality

RS Petralia, MP Mattson, PJ Yao - Ageing research reviews, 2014 - Elsevier
Here we review the examples of great longevity and potential immortality in the earliest
animal types and contrast and compare these to humans and other higher animals. We start …

Molecular phylogeny of the Platyhelminthes

J Baguñà, M Riutort - Canadian Journal of Zoology, 2004 - cdnsciencepub.com
Le phylum des plathelminthes est traditionellement considéré comme le taxon le plus basal
des organismes bilatéraux. Le problème principal avec ce positionnement est l'absence de …

A comparative analysis of planarian genomes reveals regulatory conservation in the face of rapid structural divergence

M Ivanković, JN Brand, L Pandolfini, T Brown… - Nature …, 2024 - nature.com
The planarian Schmidtea mediterranea is being studied as a model species for
regeneration, but the assembly of planarian genomes remains challenging. Here, we report …

Genome-wide analyses reveal a role for peptide hormones in planarian germline development

JJ Collins III, X Hou, EV Romanova, BG Lambrus… - PLoS …, 2010 - journals.plos.org
Bioactive peptides (ie, neuropeptides or peptide hormones) represent the largest class of
cell-cell signaling molecules in metazoans and are potent regulators of neural and …

nanos function is essential for development and regeneration of planarian germ cells

Y Wang, RM Zayas, T Guo… - Proceedings of the …, 2007 - National Acad Sciences
Germ cells are required for the successful propagation of sexually reproducing species.
Understanding the mechanisms by which these cells are specified and how their totipotency …

The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: Analysis of ESTs from the hermaphroditic strain

RM Zayas, A Hernández… - Proceedings of the …, 2005 - National Acad Sciences
Freshwater planarians have prodigious regenerative abilities that enable them to form
complete organisms from tiny body fragments. This plasticity is also exhibited by the …

Spiralian genomics and the evolution of animal genome architecture

IJY Liao, TM Lu, ME Chen, YJ Luo - Briefings in Functional …, 2023 - academic.oup.com
Recent developments in sequencing technologies have greatly improved our knowledge of
phylogenetic relationships and genomic architectures throughout the tree of life. Spiralia, a …

Molecular barcoding and phylogeography of sexual and asexual freshwater planarians of the genus Dugesia in the Western Mediterranean (Platyhelminthes …

EM Lázaro, R Sluys, M Pala, GA Stocchino… - Molecular phylogenetics …, 2009 - Elsevier
Planarians of the genus Dugesia have a worldwide distribution with high species diversity in
the Mediterranean area. In this area, populations with a triploid karyotype that reproduce by …

Conflict-reducing innovations in development enable increased multicellular complexity

J Howe, CK Cornwallis… - Proceedings of the …, 2024 - royalsocietypublishing.org
Obligately multicellular organisms, where cells can only reproduce as part of the group,
have evolved multiple times across the tree of life. Obligate multicellularity has only evolved …