Phytocannabinoids: origins and biosynthesis

T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …

Pharmacological aspects and biological effects of cannabigerol and its synthetic derivatives

F Calapai, L Cardia, E Esposito… - Evidence‐Based …, 2022 - Wiley Online Library
Cannabigerol (CBG) is a cannabinoid from the plant Cannabis sativa that lacks
psychotomimetic effects. Its precursor is the acidic form, cannabigerolic acid (CBGA), which …

Parallel evolution of cannabinoid biosynthesis

P Berman, LA de Haro, A Jozwiak, S Panda, Z Pinkas… - Nature plants, 2023 - nature.com
Modulation of the endocannabinoid system is projected to have therapeutic potential in
almost all human diseases. Accordingly, the high demand for novel cannabinoids stimulates …

Cannabis sativa bioactive compounds and their extraction, separation, purification, and identification technologies: An updated review

Y Liu, HY Liu, SH Li, W Ma, DT Wu, HB Li… - TrAC Trends in …, 2022 - Elsevier
Cannabis sativa (C. sativa) has become a worldwide plant because of its multiple bioactive
compounds with a wide range of health benefits for humans. Notably, some cannabinoid …

Analgesic potential of terpenes derived from Cannabis sativa

E Liktor-Busa, A Keresztes, J LaVigne… - Pharmacological …, 2021 - Elsevier
Pain prevalence among adults in the United States has increased 25% over the past two
decades, resulting in high health-care costs and impacts to patient quality of life. In the last …

[HTML][HTML] Recent progress in TRPM8 modulation: an update

R González-Muñiz, MA Bonache… - International journal of …, 2019 - mdpi.com
The transient receptor potential melastatin subtype 8 (TRPM8) is a nonselective, multimodal
ion channel, activated by low temperatures (< 28° C), pressure, and cooling compounds …

Cannabimimetic plants: are they new cannabinoidergic modulators?

A Kumar, M Premoli, F Aria, SA Bonini, G Maccarinelli… - Planta, 2019 - Springer
Abstract Main Conclusion Phytochemicals and secondary metabolites able to interact with
the endocannabinoid system (Cannabimimetics) have been recently described in a broad …

Evaluating the Metabolomic Profile and Anti-Pathogenic Properties of Cannabis Species

S Monyela, PN Kayoka, W Ngezimana, LE Nemadodzi - Metabolites, 2024 - mdpi.com
The Cannabis species is one of the potent ancient medicinal plants acclaimed for its
medicinal properties and recreational purposes. The plant parts are used and exploited all …

Cannabis in veterinary medicine: cannabinoid therapies for animals

JA Hartsel, K Boyar, A Pham, RJ Silver… - … in veterinary medicine, 2019 - Springer
The use of cannabis for animal species is an area of growing interest, largely due to the
therapeutic benefits being observed for humans and animals in the era of cannabis …

Unique bibenzyl cannabinoids in the liverwort Radula marginata: parallels with Cannabis chemistry

CM Andre, CE Sansom, BJ Plunkett… - New …, 2024 - Wiley Online Library
The potential of cannabinoids to address public health challenges has stimulated
exploration into alternative sources and production technologies. Radula marginata, an …