Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease

PS Bernstein, B Li, PP Vachali, A Gorusupudi… - Progress in retinal and …, 2016 - Elsevier
The human macula uniquely concentrates three carotenoids: lutein, zeaxanthin, and meso-
zeaxanthin. Lutein and zeaxanthin must be obtained from dietary sources such as green …

Microalgal derivatives as potential nutraceutical and food supplements for human health: A focus on cancer prevention and interception

C Galasso, A Gentile, I Orefice, A Ianora, A Bruno… - Nutrients, 2019 - mdpi.com
Epidemiological studies are providing strong evidence on beneficial health effects from
dietary measures, leading scientists to actively investigate which foods and which specific …

Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health

ESM Abdel-Aal, H Akhtar, K Zaheer, R Ali - Nutrients, 2013 - mdpi.com
The eye is a major sensory organ that requires special care for a healthy and productive
lifestyle. Numerous studies have identified lutein and zeaxanthin to be essential …

Review of methods for analysis of carotenoids

KT Amorim-Carrilho, A Cepeda, C Fente… - TrAC Trends in Analytical …, 2014 - Elsevier
This review covers current analytical techniques, instruments and methodologies used in the
analysis of carotenoids in foods and human samples. We also cover the importance of …

Intakes of lutein, zeaxanthin, and other carotenoids and age-related macular degeneration during 2 decades of prospective follow-up

J Wu, E Cho, WC Willett, SM Sastry… - JAMA …, 2015 - jamanetwork.com
Importance Despite strong biological plausibility, evidence from epidemiologic studies and
clinical trials on the relations between intakes of lutein and zeaxanthin and age-related …

Stress induced production of plant secondary metabolites in vegetables: functional approach for designing next generation super foods

D Sharma, B Shree, S Kumar, V Kumar… - Plant Physiology and …, 2022 - Elsevier
Plant secondary metabolites are vital for human health leading to the gain the access to
natural products. The quality of crops is the result of the interaction of different biotic and …

Retinal light toxicity

PN Youssef, N Sheibani, DM Albert - Eye, 2011 - nature.com
The ability of light to enact damage on the neurosensory retina and underlying structures
has been well understood for hundreds of years. While the eye has adapted several …

Effects of fish n-3 PUFAs on intestinal microbiota and immune system

C Parolini - Marine drugs, 2019 - mdpi.com
Studies over several decades have documented the beneficial actions of n-3
polyunsaturated fatty acids (PUFAs), which are plentiful in fish oil, in different disease states …

A systematic review of carotenoids in the management of age-related macular degeneration

DW Lem, PG Davey, DL Gierhart, RB Rosen - Antioxidants, 2021 - mdpi.com
Age-related macular degeneration (AMD) remains a leading cause of modifiable vision loss
in older adults. Chronic oxidative injury and compromised antioxidant defenses represent …

Chitosan-oleic acid-sodium alginate a hybrid nanocarrier as an efficient delivery system for enhancement of lutein stability and bioavailability

V Toragall, N Jayapala, B Vallikannan - International journal of biological …, 2020 - Elsevier
Lutein is a hydrophobic antioxidant carotenoid with proven retinal and macular protection
against oxidative stress. However, low aqueous solubility and bioavailability limit its clinical …