Pre-eclampsia

E Dimitriadis, DL Rolnik, W Zhou… - Nature reviews Disease …, 2023 - nature.com
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Regulation of maternal–fetal metabolic communication

CE Bowman, Z Arany, MJ Wolfgang - Cellular and molecular life sciences, 2021 - Springer
Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome‐Induced Pyroptosis via Inhibiting the TLR4/NF‐κB/PFKFB3 Signaling in …

Y Zhang, W Liu, Y Zhong, Q Li, M Wu… - Oxidative Medicine …, 2021 - Wiley Online Library
NOD‐like receptor family, pyrin domain‐containing protein 3 (NLRP3) inflammasome‐
mediated pyroptosis is a crucial event in the preeclamptic pathogenesis, tightly linked with …

Potential biomarkers for late-onset and term preeclampsia: A sco** review

L Han, OJ Holland, F Da Silva Costa… - Frontiers in …, 2023 - frontiersin.org
Preeclampsia is a progressive, multisystem pregnancy disorder. According to the time of
onset or delivery, preeclampsia has been subclassified into early-onset (< 34 weeks) and …

Revisiting preeclampsia: a metabolic disorder of the placenta

M Hu, J Li, PN Baker, C Tong - The FEBS journal, 2022 - Wiley Online Library
Preeclampsia (PE) is a leading cause of maternal and neonatal mortality and morbidity
worldwide, impacting the long‐term health of both mother and offspring. PE has long been …

Preeclampsia: from cellular wellness to inappropriate cell death, and the roles of nutrition

AW Lokeswara, R Hiksas, R Irwinda… - Frontiers in Cell and …, 2021 - frontiersin.org
Preeclampsia is one of the most common obstetrical complications worldwide. The
pathomechanism of this disease begins with abnormal placentation in early pregnancy …

[HTML][HTML] Proteomics and metabolomics profiling of platelets and plasma mediators of thrombo-inflammation in gestational hypertension and preeclampsia

LGN de Almeida, D Young, L Chow, J Nicholas, A Lee… - Cells, 2022 - mdpi.com
Platelets may be pivotal mediators of the thrombotic and coagulopathic complications of
preeclampsia (PE), linking inflammation and thrombosis with endothelial and vascular …

A review of omics approaches to study preeclampsia

PA Benny, FM Alakwaa, RJ Schlueter, CB Lassiter… - Placenta, 2020 - Elsevier
Preeclampsia is a medical condition affecting 5–10% of pregnancies. It has serious effects
on the health of the pregnant mother and develo** fetus. While possible causes of …

Identification of biomarkers for preeclampsia based on metabolomics

M Yao, Y **ao, Z Yang, W Ge, F Liang, H Teng… - Clinical …, 2022 - Taylor & Francis
Background Preeclampsia (PE) is a significant cause of maternal and neonatal morbidity
and mortality worldwide. However, the pathogenesis of PE is unclear and reliable early …

Early HbA1c levels as a predictor of adverse obstetric outcomes: a systematic review and Meta-analysis

L Mañé, H Navarro, J Pedro-Botet, JJ Chillarón… - Journal of clinical …, 2024 - mdpi.com
Background: The objective was to assess the association between early HbA1c levels and
pregnancy complications and whether this relationship is affected when HbA1c thresholds …