Gut-microbiota-derived metabolites maintain gut and systemic immune homeostasis

J Wang, N Zhu, X Su, Y Gao, R Yang - Cells, 2023 - mdpi.com
The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …

The lung microbiome: progress and promise

SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

Dietary fiber confers protection against flu by sha** Ly6c− patrolling monocyte hematopoiesis and CD8+ T cell metabolism

A Trompette, ES Gollwitzer, C Pattaroni… - Immunity, 2018 - cell.com
Dietary fiber protects against chronic inflammatory diseases by dampening immune
responses through short-chain fatty acids (SCFAs). Here we examined the effect of dietary …

[HTML][HTML] Pro-and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

M Li, BCAM Van Esch, GTM Wagenaar… - European journal of …, 2018 - Elsevier
In the gastro-intestinal tract, short chain fatty acids (SCFAs) have protective effects on
epithelial cells. However, their effects on inflammatory cytokine production by endothelial …

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

M Sun, W Wu, Z Liu, Y Cong - Journal of gastroenterology, 2017 - Springer
Gut microbiota has been well recognized in regulation of intestinal homeostasis and
pathogenesis of inflammatory bowel diseases. However, the mechanisms involved are still …

The gut-bone axis: how bacterial metabolites bridge the distance

MM Zaiss, RM Jones, G Schett… - The Journal of clinical …, 2019 - Am Soc Clin Investig
The gut microbiome is a key regulator of bone health that affects postnatal skeletal
development and skeletal involution. Alterations in microbiota composition and host …

A cross-talk between microbiota-derived short-chain fatty acids and the host mucosal immune system regulates intestinal homeostasis and inflammatory bowel …

P Gonçalves, JR Araújo… - Inflammatory bowel …, 2018 - academic.oup.com
Gut microbiota has a fundamental role in the energy homeostasis of the host and is essential
for proper “education” of the immune system. Intestinal microbial communities are able to …

[HTML][HTML] Butyrate ameliorates chronic alcoholic central nervous damage by suppressing microglia-mediated neuroinflammation and modulating the microbiome-gut …

H Wei, C Yu, C Zhang, Y Ren, L Guo, T Wang… - Biomedicine & …, 2023 - Elsevier
Background Alcohol abuse triggers neuroinflammation, leading to neuronal damage and
further memory and cognitive impairment. Few satisfactory advances have been made in the …

The gut microbiome in hypertension: recent advances and future perspectives

EG Avery, H Bartolomaeus, A Maifeld, L Marko… - Circulation …, 2021 - Am Heart Assoc
The pathogenesis of hypertension is known to involve a diverse range of contributing factors
including genetic, environmental, hormonal, hemodynamic and inflammatory forces, to …

Short chain fatty acids in human gut and metabolic health

EE Blaak, EE Canfora, S Theis, G Frost… - Beneficial …, 2020 - wageningenacademic.com
Evidence is accumulating that short chain fatty acids (SCFA) play an important role in the
maintenance of gut and metabolic health. The SCFA acetate, propionate and butyrate are …