While the number of sequenced genomes continues to grow, experimentally verified
functional annotation of whole genomes remains patchy. Structural genomics projects are …

Abstract Cys2-His2 (C2H2) zinc finger domains (ZFs) were originally identified as DNA-
binding domains, and uncharacterized domains are typically assumed to function in DNA …

Domestic yaks (Bos grunniens) provide meat and other necessities for Tibetans living at
high altitude on the Qinghai-Tibetan Plateau and in adjacent regions. Comparison between …

We determined the genome sequence of sweet cherry (Prunus avium) using next-
generation sequencing technology. The total length of the assembled sequences was 272.4 …

Functional genomics technologies have been widely adopted in the biological research of
both model and non-model species. An efficient functional annotation of DNA or protein …

Abstract The InterPro database (http://www. ebi. ac. uk/interpro/) integrates together
predictive models or 'signatures' representing protein domains, families and functional sites …

Homology modeling aims to build three-dimensional protein structure models using
experimentally determined structures of related family members as templates. SWISS …

Polar bears are uniquely adapted to life in the High Arctic and have undergone drastic
physiological changes in response to Arctic climates and a hyperlipid diet of primarily …

Background Worldwide, grapes and their derived products have a large market. The
cultivated grape species Vitis vinifera has potential to become a model for fruit trees …

Protein secretion is a common property of pathogenic microbes. Gram-negative bacterial
pathogens use at least 6 distinct extracellular protein secretion systems to export proteins …