Urease is a nickel-dependent metalloenzyme found in plants, some bacteria, and fungi.
Bacterial enzyme is of special importance since it has been demonstrated as a potent …

(acyl/aroyl)-3-(substituted) thioureas are exciting structures in the fields of organic synthesis,
material sciences, and biomedical research. Of particular significance is the fact that acyl …

A novel synthetic reaction was employed to produce an acridine derivative of 4-ethyl
acridine-1, 3, 9 (2, 4, 10H)-trione. The structural characterizations of the synthesized …

Sulfonamide derivatives serve as an important building blocks in the drug design discovery
and development (4D) process. Ciprofloxacin-, sulfadiazine-and amantadine-based …

This study was carried out to identify the synthesis of a new group of thiazole-linked
thioureas with aromatic and aliphatic side chains (4a–k) using a one-pot three-component …

Blocking the catalytic activity of urease has been shown to have a key role in different
diseases as well as in different agricultural applications. A vast array of molecules have …

Abstract Two copper (II) complexes,[Cu2 (L1) 2]· 2H2O (1) and [Cu3 (L1) 2 (NCS) 2](2), and
two nickel (II) complexes,[NiL2 (NCS)](3) and [Ni (L2) 2 (NCS)]· CH3OH (4), were prepared …

The inhibitory action of Schiff base complexes of 3d metals against the urease enzyme is
well explored in the scientific community. However, the ability of such complexes in …

Present work aimed to synthesize some unique bi-heterocyclic benzamides as lead
compounds for the in vitro inhibition of urease enzyme, followed by in silico studies. These …

Expressed by a variety of plants, fungi and bacteria, the urease enzyme is directly
associated with the virulence factor of many bacteria, including Helicobacter pylori, a gram …