Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Ageing and age-related diseases share some basic mechanistic pillars that largely
converge on inflammation. During ageing, chronic, sterile, low-grade inflammation—called …

Among other mechanisms, oxidative stress has been postulated to play an important role in
the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential …

The role of mitochondrial function in health and disease has become increasingly
recognized, particularly in the last two decades. Mitochondrial dysfunction as well as …

Many approaches have been used in the effective management of type 2 diabetes mellitus.
A recent paradigm shift has focused on the role of adipose tissues in the development and …

Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated
as byproducts of oxidative phosphorylation in the mitochondria or via cell signaling-induced …