Detecting structural progression in glaucoma with optical coherence tomography

AJ Tatham, FA Medeiros - Ophthalmology, 2017 - Elsevier
Optical coherence tomography (OCT) is increasingly used to obtain objective measurements
of the retinal nerve fiber layer (RNFL), optic nerve head, and macula for assessing glaucoma …

Detection and measurement of clinically meaningful visual field progression in clinical trials for glaucoma

CG De Moraes, JM Liebmann, LA Levin - Progress in retinal and eye …, 2017 - Elsevier
Glaucomatous visual field progression has both personal and societal costs and therefore
has a serious impact on quality of life. At the present time, intraocular pressure (IOP) is …

[HTML][HTML] Detailed vascular anatomy of the human retina by projection-resolved optical coherence tomography angiography

JP Campbell, M Zhang, TS Hwang, ST Bailey… - Scientific reports, 2017 - nature.com
Optical coherence tomography angiography (OCTA) is a noninvasive method of 3D imaging
of the retinal and choroidal circulations. However, vascular depth discrimination is limited by …

Corneal hysteresis as a risk factor for glaucoma progression: a prospective longitudinal study

FA Medeiros, D Meira-Freitas, R Lisboa, TM Kuang… - Ophthalmology, 2013 - Elsevier
Purpose To evaluate the role of corneal hysteresis (CH) as a risk factor for the rate of visual
field progression in a cohort of patients with glaucoma followed prospectively over time …

Optical coherence tomography angiography in glaucoma: a review

L Van Melkebeke, J Barbosa-Breda, M Huygens… - Ophthalmic …, 2018 - karger.com
Background: Glaucoma is the leading cause of irreversible blindness worldwide. Several
techniques exist for the diagnosis and follow-up of patients. Optical coherence tomography …

Rates of retinal nerve fiber layer thinning in glaucoma suspect eyes

A Miki, FA Medeiros, RN Weinreb, S Jain, F He… - Ophthalmology, 2014 - Elsevier
Purpose To compare the rates of retinal nerve fiber layer (RNFL) loss in patients suspected
of having glaucoma who developed visual field damage (VFD) with those who did not …

Longitudinal changes in quality of life and rates of progressive visual field loss in glaucoma patients

FA Medeiros, CPB Gracitelli, ER Boer, RN Weinreb… - Ophthalmology, 2015 - Elsevier
Purpose To evaluate the association between longitudinal changes in quality of life (QoL)
and rates of progressive visual field loss in glaucoma. Design Prospective observational …

[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Comparison of glaucoma progression detection by optical coherence tomography and visual field

X Zhang, A Dastiridou, BA Francis, O Tan… - American journal of …, 2017 - Elsevier
Purpose To compare longitudinal glaucoma progression detection using optical coherence
tomography (OCT) and visual field (VF). Design Validity assessment. Methods We analyzed …

[HTML][HTML] Retinal nerve fiber layer features identified by unsupervised machine learning on optical coherence tomography scans predict glaucoma progression

M Christopher, A Belghith, RN Weinreb… - … & visual science, 2018 - tvst.arvojournals.org
Purpose: To apply computational techniques to wide-angle swept-source optical coherence
tomography (SS-OCT) images to identify novel, glaucoma-related structural features and …