While the first time-of-flight (TOF)-positron emission tomography (PET) systems were already
built in the early 1980s, limited clinical studies were acquired on these scanners. PET was …

Time-of-flight (TOF) PET was initially introduced in the early days of PET. The TOF PET
scanners developed in the 1980s had limited sensitivity and spatial resolution, were …

We present a new version of STIR (Software for Tomographic Image Reconstruction), an
open source object-oriented library implemented in C++ for 3D positron emission …

Significant improvements have made it possible to add the technology of time-of-flight (TOF)
to improve PET, particularly for oncology applications. The goals of this work were to …

In tomographic medical imaging (PET, SPECT, CT), differences in data acquisition and
organization are a major hurdle for the development of tomographic reconstruction software …

In emission tomography statistically based iterative methods can improve image quality
relative to analytic image reconstruction through more accurate physical and statistical …

Positron emission tomography (PET) is a tool for metabolic imaging that has been utilized
since the earliest days of nuclear medicine. A key component of such imaging systems is the …

This paper provides a review and an update on time-of-flight PET imaging with a focus on
PET instrumentation, ranging from hardware design to software algorithms. We first present …

We proposed a concept of whole gamma imaging (WGI) that utilizes all detectable gamma
rays for imaging. An additional detector ring, which is used as the scatterer, is inserted in the …

As photon-counting imaging systems become more complex, there is a trend toward
measuring more attributes of each individual event. In various imaging systems the attributes …