Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) is an enzyme and a very omnipresent zinc
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …

Thiazole derivatives remains honored heterocycles in the field of medicinal chemistry. This
scaffold has been proven as a universal motif that is present in numerous pharmacologically …

In this study, a series of novel bromophenols were synthesized from benzoic acids and
methoxylated bromophenols. The synthesized compounds were evaluated by using different …

Some novel derivatives of thiosemicarbazide and 1, 2, 4‐triazole‐3‐thiol were synthesized
and evaluated for their biological activities. The title compounds were prepared starting from …

A series of novel phloroglucinol derivatives were designed, synthesized, characterized
spectroscopically and tested for their inhibitory activity against selected metabolic enzymes …

In the present study, a series of new hybrid compounds containing chalcone and
methanoisoindole units 7a-n ((3aR, 4S, 7R, 7aS)-2-(4-((E)-3-(3-aryl) acryloyl) phenyl)-3a, 4 …

Herein, a series of isoindole‐1, 3‐dione substituted sulfonamide derivatives (3, 4 a–k) were
designed, synthesized, and biologically evaluated, as inhibitors of carbonic anhydrase (CA) …

The drug resistance became the major challenge in the antimicrobial and anticancer drugs
therapy. Therefore, there is an urgent need to looking for new types of antimicrobial and …

Fungal infections are posing serious threat to healthcare system due to emerging resistance
among available antifungal agents. Among available antifungal agents in clinical practice …